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Hypothyroidism is defined as an underactive thyroid gland and one of the reasons for inadequate stimulation of thyroid is dysfunction of the hormone regulating brain centers. Olfaction disorders have been considered as a problem in hypothyroidism. It has been hypothesized that olfaction disorders reduce olfactory stimulation and diminished olfactory ...
N. Aydın+7 more
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Drosophila olfaction as a model system for studying human neurological disorders
Journal of Biosciences, 2023The fruit fly, Drosophila melanogaster, has been one of the finest systems for decoding myriad puzzles across different domains of biology. Beyond addressing the fundamental problems, it has been used as a fantastic model organism for human disease research.
Subhajit Sarkar, Abhijit Das
semanticscholar +3 more sources
Olfaction deterioration in cognitive disorders in the elderly
Aging Clinical and Experimental Research, 2016Parkinson's and Alzheimer's diseases are widespread neurodegenerative pathologies. Parkinson's disease affects about 1 % of the population over the age of 65 years, while Alzheimer is considered the most common cause of dementia, with an annual incidence of 1 % in persons aged 65 years.
G. Ottaviano+3 more
semanticscholar +3 more sources
Olfactory system plays a principal role of sense of odor. Olfactory dysfunction has been observed in various conditions, including aging, neurological disorders, and neuropsychiatric disorders.
D. Meshram, Dipti D. Patil
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How olfaction disorders can cause depression? The role of habenular degeneration
Neuroscience, 2013The removal of bilateral olfactory bulbs (OBs) can result in serious behavioral, neurochemical, neuroendocrine, and neuroimmune alterations in depressed patients. However, there is little information on how olfactory bulbectomy (OBX) leads to depression.
E. Oral+6 more
semanticscholar +4 more sources
Olfaction in Aging and Medical Disorders
Considerable shifts in demographics are taking place on a global scale, and the most significant change is a massive increase in the elderly population. This shift will present challenges to medical practitioners because the elderly have special sensory and nutritional needs that must be taken into account when providing medical care.
Susan S. Schiffman
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Olfaction in Affective and Anxiety Disorders: A Review of the Literature
Psychopathology, 2012<b><i>Background:</i></b> Olfaction and its relation to mental health is an area of growing interest. Brain areas linked to olfaction partially overlap with brain areas involved in psychiatric disorders; consequently, the study of olfactory function allows us to explore the integrity of these brain areas with a non-invasive and ...
Emma Burón, A. Bulbena
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Olfaction in neurodegenerative disorder
AbstractThere has been an increase of interest in olfactory dysfunction since it was realised that anosmia was a common feature of idiopathic Parkinson's disease (PD) and Alzheimer‐type dementia (AD). It is an intriguing possibility that the first sign of a disorder hitherto regarded as one of movement or cognition may be that of disturbed smell sense.
Christopher H. Hawkes
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A systematic review on olfaction in child and adolescent psychiatric disorders
Journal of Neural Transmission, 2012There is substantial evidence that olfactory function may serve as biomarker in adult neuropsychiatric disorders, e.g. overall diminished olfaction in Parkinson's disease as parameter for early pre-motor and differential diagnosis. Here, we present data from a systematic literature review in olfactory function in child and adolescent psychiatric ...
M. Schecklmann+6 more
semanticscholar +4 more sources