Results 121 to 130 of about 51,216 (167)

Farnesyl Diphosphate Synthase Promotes Proliferation of Hepatocellular Carcinoma Cells by Interacting With Glucose‐6‐Phosphate Dehydrogenase

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is a highly aggressive malignancy characterized by metabolic reprogramming that supports tumour growth and survival. This study identifies farnesyl diphosphate synthase (FDPs), a key enzyme in the mevalonate pathway, as a critical regulator of HCC proliferation and apoptosis.
Jingfeng Liu, Yisheng Zhu, Jiyang Lv, Xiaohao Hu, Yan Zhong   +4 more
wiley   +1 more source

Non-cell-autonomous control of mouse gastruloid development by the ultra-conserved lncRNA T-UCstem1. [PDF]

EMBO J
Coppola A, Amoroso F, Saracino F, Andolfi G, Sozzi E, Salerno P, Zoppoli P, Fiorenzano A, Merla G, Patriarca EJ, Minchiotti G, Fico A.   +11 more
europepmc   +1 more source

Gene Regulatory Programs of NK Cells Show That NCAM1 (CD56) and KIRs Are Controlled by Genetically Polymorphic Distal Regulatory Elements

European Journal of Immunology, Volume 56, Issue 2, February 2026.
A deeper understanding of the natural killer cell gene expression regulation driving NK cell maturation and cytotoxicity could provide critical insights into optimizing NK therapies. Our findings reveal novel enhancers governing NK cell genes for NCAM1/CD56 and cis‐regulation for KIR receptors and clarify existing models of NK cell cis‐accessibility ...
Mariam A. Salem, Aditi Varkey, Matthew D. Estrada, Kruthika Sharma, Caprice D. Eisele, Nitin Chakravarti, Dean A. Lee, Aharon G. Freud, Bethany L. Mundy‐Bosse, Patrick L. Collins   +9 more
wiley   +1 more source

IS<i>Apl4</i>, a New IS<i>1595</i> Family Insertion Sequence Forming a Novel Pseudo-Compound Transposon That Confers Antimicrobial Multidrug Resistance in <i>Actinobacillus pleuropneumoniae</i>. [PDF]

Antibiotics (Basel)
Bossé JT, Li Y, Stegger M, Cohen LM, Angen Ø, Overballe-Petersen S, Hanke D, Schwarz S, Langford PR, Krüger-Haker H.   +9 more
europepmc   +1 more source

Recent Advances in Integrating Graphene into Polymeric Nanocomposite Hydrogels for Biomedical Applications

Macromolecular Bioscience, Volume 26, Issue 2, February 2026.
This review explores recent progress in graphene‐based polymeric nanocomposite hydrogels and how they enhance mechanical strength, electrical conductivity, and biocompatibility. It outlines key fabrication strategies and highlights applications in drug delivery, tissue engineering, and photothermal therapy, while also discussing the emerging role of ...
Abrar Hussain, Irum Batool, Khurram Shahzad, Syed Kumail Hussain Naqvi, Shahzaib Akhter, Ujala Zafar, Khaled Chawraba, Sang Hyun Park   +7 more
wiley   +1 more source

Whole Genome Development of Specific Alien-Chromosome Oligo (SAO) Markers for Wild Peanut Chromosomes Based on Chorus2. [PDF]

Plants (Basel)
Sun H, Jiang C, Qi W, Chen Y, Song X, Wang C, Yu J, Yuan G.   +7 more
europepmc   +1 more source

Deciphering mRNA Translation During Sperm Capacitation: A New Frontier in Fertility Research

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Male infertility accounts for approximately 50% of infertility cases, with nearly 30% remaining unexplained after standard evaluations. This highlights the need for a better understanding of sperm function to advance diagnostic and therapeutic strategies. Sperm were long considered translationally quiescent; however, emerging evidence suggests
Saurabh Tiwari, Nehal Thakor, Jacob Thundathil   +2 more
wiley   +1 more source

Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution. [PDF]

Cell
Cheng Y, Dang S, Zhang Y, Chen Y, Yu R, Liu M, Jin S, Han A, Katz S, Wang S.   +9 more
europepmc   +1 more source

Twists and Turns of Liquid Crystals Unravelled by Small‐Angle Scattering

Small Methods, Volume 10, Issue 3, 9 February 2026.
X‐ray scattering provides valuable insights into material structure and self‐assembly. This review discusses the use of small‐ and wide‐angle X‐ray scattering (SWAXS) as well as grazing incident SWAXS for examining self‐assembled systems, especially liquid crystals.
Jessie Wong, Jean‐Luc Brousseau, Hatem M. Titi   +2 more
wiley   +1 more source

Chiral Bifacial Non‐Fullerene Acceptors with Chirality‐Induced Spin Selectivity: A Homochiral Strategy to Improve Organic Solar Cell Performance

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
We develop new bifacial chiral non‐fullerene acceptors (NFAs) for organic solar cells (OSCs). Through comparative investigations of four NFAs including meso, racemic, and chiral entries, we demonstrate the superiority of homochiral NFAs for the first time.
Shuang Li, Fumitaka Ishiwari, Shaoxian Li, Yumi Yakiyama, Akinori Saeki   +4 more
wiley   +2 more sources