Results 121 to 130 of about 54,454 (186)

Transcriptional Regulation of HSP60, HSP70, and HSP90 in Response to Selenium Nanoparticles and Sodium Selenite in Periparturient Cloned Saanen Goats and Their Offspring

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Selenium nanoparticles (SeNPs) outperform sodium selenite in raising serum selenium levels and suppressing HSP60, HSP70, and HSP90 transcription in periparturient goats and their offspring, indicating reduced cellular stress regardless of cloning status.
Gholam‐Ali Kojouri, Hossein Hassanpour, Ahmad Yousefi   +2 more
wiley   +1 more source

Mitochondrial dysfunction activates ADAMTS-5 expression via mt-dsRNA-PKR-Spi-1 axis in osteoarthritic chondrocytes. [PDF]

iScience
Mu Y, Yan S, Wang Y, Liang B, Tang R, Yang H, Ma L, Zhang Y, Li D.   +8 more
europepmc   +1 more source

Brine Pool Microbes Enrich Metalliferous Sediments in Salt Giant Basins

AGU Advances, Volume 7, Issue 6, September 2026.
Abstract We report the discovery of an extinct deep‐sea brine pool in the Red Sea's Hume Deep, providing evidence that rift‐shoulder pools are ephemeral on millennial timescales, and that the microbially‐enriched metalliferous deposits produced during the pool's active phase persist into the stratigraphic record.
Morgan I. Chakraborty, Hannah Shernisky, Clément G. L. Pollier, Amanda M. Oehlert, Arash Sharifi, Ali Pourmand, Bolton J. Howes, Benjamin Minch, Mohammad Moniruzzaman, Larissa Frühe, Mattie Rodrigue, Sam J. Purkis   +11 more
wiley   +1 more source

Disruption of a six-nucleotide miRNA motif improves PKD1 dosage and ameliorates polycystic kidney disease. [PDF]

Nucleic Acids Res
Lakhia R, Song C, Biggers L, Zumwalt M, Alvarez J, Somasundaram A, Ramalingam H, Cobo-Stark P, Patel V.   +8 more
europepmc   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, Volume 293, Issue 17, Page 5149-5169, September 2026.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Analysis of <i>cis</i> Elements in the <i>mp50</i> mRNA of <i>Trichomonas vaginalis</i>. [PDF]

Microorganisms
Villalpando-Aguilar JL, Figueroa-Angulo EE, Salazar-Pedreguera LA, Castillo-Hernández EG, Alvarez-Sánchez ME.   +4 more
europepmc   +1 more source

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

The FEBS Journal, Volume 293, Issue 17, Page 5205-5220, September 2026.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar, Siarhei Paliavoi, Barbora Stefanovie, Jan Josef Palecek   +3 more
wiley   +1 more source

BN-embedded oligo- and poly(thiophene iminoborane)s: dipole-aligned isosteres of poly(thiophene vinylene) with efficient room-temperature phosphorescence. [PDF]

Chem Sci
Chorbacher J, Derra T, Klopf J, Friedrich A, Helten H.   +4 more
europepmc   +1 more source

Integrative Long‐Read Multi‐Omics of a Patient With GPI Deficiency: A Molecular Case Study of a Candidate Dual‐Effect GPI Variant

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT The molecular determinants of phenotypic severity in red cell enzymopathies are often obscured by the disconnect between coding sequence variants and their regulatory landscapes. Here we present a single‐patient molecular case study that uses an integrative multi‐omic approach—combining short‐read WGS, PacBio HiFi long‐read sequencing, native ...
Ireneusz Stolarek, Joanna Delimata‐Raczek, Natalia Koralewska, Klaudia Sikora, Magdalena Rakoczy, Małgorzata Marcinkowska‐Swojak, Luiza Handschuh, Jarosław Czyż, Marek Figlerowicz   +8 more
wiley   +1 more source

Adaptive laboratory evolution of Lactiplantibacillus plantarum enhances furan tolerance and lactic acid production in lignocellulosic hydrolysate. [PDF]

Bioresour Bioprocess
Sharma S, Surve SV, Fernandes JM, Mahale V, Vijayvargiya M, Kulkarni R.   +5 more
europepmc   +1 more source