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High pressure liquid chromatography of oligodeoxyribonucleotides
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973Abstract A high pressure liquid chromatography system capable of resolving oligodeoxy-ribonucleotides of intermediate size is described. Columns filled with a pellicular weak anion exchanger consisting of a polymeric aliphatic amine permit the rapid resolution of small amounts of oligomers.
A. de Czekala+6 more
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Synthesis of phospholipid-oligodeoxyribonucleotide conjugates
Tetrahedron Letters, 1995Abstract Chemical synthesis of modified phospholipids and their attachment to oligodeoxyribonucleotides via dithiolinker is described.
Serguei V. Vinogradov+2 more
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ChemInform Abstract: Solid Phase Synthesis of Cyclic Oligodeoxyribonucleotides.
ChemInform, 1987Abstract The polymer supported synthesis of cyclic oligomers of deoxycytidilic acid is described, by a method based on an oligonucleotide-solid phase linkage through the amino group of the base.
S. BARBATO+4 more
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Use of an aminooxy linker for the functionalization of oligodeoxyribonucleotides
Bioorganic & Medicinal Chemistry Letters, 2001We describe the preparation of oligonucleotides containing a 5'-linker bearing an aminooxy group. Use of the trityl protecting group for the aminooxy moiety allows purification of the modified oligonucleotide by reverse phase HPLC and cleavage in mild acidic conditions. Derivatization with an aldehydic reporter group is efficient and rapid.
Eric Defrancq, Jean Lhomme
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Structural requirements and applications of inhibitory oligodeoxyribonucleotides
Immunologic Research, 2007Synthetic oligodeoxyribonucleotides (ODN) bearing certain sequence characteristics mimic bacterial DNA by activating B cells and dendritic cells through Toll-like receptor (TLR) 9, an event that potentiates both humoral and cell-mediated immunity. ODN sharing some of the sequence characteristics of strong stimulatory (ST-) ODN, but substituting GGG for
Robert F. Ashman, Petar Lenert
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Sequence analysis of oligodeoxyribonucleotides by mass spectrometry
Analytical Biochemistry, 1973Abstract Low-resolution mass spectra have been obtained on the following general types of mono-, di-, tetra,- and hexa-deoxyribonucleotides: pX, Xp, XpY, pXpY, pXp, pXpYp, pXpYpXpY and on trifluoroacetylated XpY, YpX, pXpYpXpY, XpYpXpY, and XpYpXpYpXpY (where X and Y indicate the purine and pyrimidine nucleosides, cytidine, thymidine, adenosine, or ...
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A New Approach to the Synthesis of Oligodeoxyribonucleotides
Angewandte Chemie International Edition in English, 1973Walter Heidmann, Hubert Köster
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Sequence Analysis of Oligodeoxyribonucleotides
1994Peter T. Gilham, Diane M. Black
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Rapid synthesis of oligodeoxyribonucleotides
Tetrahedron Letters, 1979Roberto Crea+2 more
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