Results 221 to 230 of about 15,454 (234)
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High pressure liquid chromatography of oligodeoxyribonucleotides

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973
Abstract A high pressure liquid chromatography system capable of resolving oligodeoxy-ribonucleotides of intermediate size is described. Columns filled with a pellicular weak anion exchanger consisting of a polymeric aliphatic amine permit the rapid resolution of small amounts of oligomers.
A. de Czekala   +6 more
openaire   +3 more sources

Synthesis of phospholipid-oligodeoxyribonucleotide conjugates

Tetrahedron Letters, 1995
Abstract Chemical synthesis of modified phospholipids and their attachment to oligodeoxyribonucleotides via dithiolinker is described.
Serguei V. Vinogradov   +2 more
openaire   +2 more sources

ChemInform Abstract: Solid Phase Synthesis of Cyclic Oligodeoxyribonucleotides.

ChemInform, 1987
Abstract The polymer supported synthesis of cyclic oligomers of deoxycytidilic acid is described, by a method based on an oligonucleotide-solid phase linkage through the amino group of the base.
S. BARBATO   +4 more
openaire   +4 more sources

Use of an aminooxy linker for the functionalization of oligodeoxyribonucleotides

Bioorganic & Medicinal Chemistry Letters, 2001
We describe the preparation of oligonucleotides containing a 5'-linker bearing an aminooxy group. Use of the trityl protecting group for the aminooxy moiety allows purification of the modified oligonucleotide by reverse phase HPLC and cleavage in mild acidic conditions. Derivatization with an aldehydic reporter group is efficient and rapid.
Eric Defrancq, Jean Lhomme
openaire   +3 more sources

Structural requirements and applications of inhibitory oligodeoxyribonucleotides

Immunologic Research, 2007
Synthetic oligodeoxyribonucleotides (ODN) bearing certain sequence characteristics mimic bacterial DNA by activating B cells and dendritic cells through Toll-like receptor (TLR) 9, an event that potentiates both humoral and cell-mediated immunity. ODN sharing some of the sequence characteristics of strong stimulatory (ST-) ODN, but substituting GGG for
Robert F. Ashman, Petar Lenert
openaire   +3 more sources

Sequence analysis of oligodeoxyribonucleotides by mass spectrometry

Analytical Biochemistry, 1973
Abstract Low-resolution mass spectra have been obtained on the following general types of mono-, di-, tetra,- and hexa-deoxyribonucleotides: pX, Xp, XpY, pXpY, pXp, pXpYp, pXpYpXpY and on trifluoroacetylated XpY, YpX, pXpYpXpY, XpYpXpY, and XpYpXpYpXpY (where X and Y indicate the purine and pyrimidine nucleosides, cytidine, thymidine, adenosine, or ...
openaire   +3 more sources

A New Approach to the Synthesis of Oligodeoxyribonucleotides

Angewandte Chemie International Edition in English, 1973
Walter Heidmann, Hubert Köster
openaire   +3 more sources

Rapid synthesis of oligodeoxyribonucleotides

Tetrahedron Letters, 1979
Roberto Crea   +2 more
openaire   +2 more sources

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