Results 31 to 40 of about 294 (134)

Oligodontia with taurodontism in monozygous twins

North American Journal of Medical Sciences, 2012
Dear Editor, A wide spectrum of developmental pathologies affects the teeth, which includes variation in shape, size, eruption pattern, and number. Tooth agenesis is one such condition that leads to hypodontia and oligodontia. Prevalence of hypodontia was found to be 1.6% to 9.6% in the permanent dentition.
Kandagal, V Suresh, Bilahari, N, Shenai, Prashanth, Chatra, Laxmikanth, Pramod, R C, Ashir, K R   +5 more
openaire   +3 more sources

The oligodontia phenotype in a X-linked hypohidrotic ectodermal dysplasia patient with a novel EVC2 variant

Heliyon
Objectives: To analyse the pathogenic genes in a patient with hypohidrotic ectodermal dysplasia (HED) and explore the relationship between pathogenic genes and the oligodontia phenotype.
Yi Wu, Jing Sun, Caiqi Zhang, Siyuan Ma, Yiting Liu, Xiaoshan Wu, Qingping Gao   +6 more
doaj   +1 more source

Mutations in WNT10B Are Identified in Individuals with Oligodontia [PDF]

The American Journal of Human Genetics, 2016
Supplemental Data Supplemental Data include six figures and three tables and can be found with this article online at http://dx.doi.org/10.1016/j.ajhg.2016.05.012. Supplemental Data Document S1. Figures S1–S6 and Tables S1–S3 Download Document S2.
Yu, Ping, Yang, Wenli, Han, Dong, Wang, Xi, Guo, Sen, Li, Jinchen, Li, Fang, Zhang, Xiaoxia, Wong, Sing-Wai, Bai, Baojing, Liu, Yao, Du, Jie, Sun, Zhong Sheng, Shi, Songtao, Feng, Hailan, Cai, Tao   +15 more
openaire   +2 more sources

Management of extraction sites: From biological principles to clinical practice

Periodontology 2000, EarlyView.
Abstract Objectives To provide a concise overview of the biological events and dimensional changes following tooth extraction and to summarize current therapeutic strategies for extraction site management, including alveolar ridge preservation (ARP), alveolar ridge reconstruction (ARR), partial extraction therapies (PET), and tooth autotransplantation (
Emilio Couso‐Queiruga, Gustavo Avila‐Ortiz   +1 more
wiley   +1 more source

Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population. [PDF]

PLoS ONE, 2013
BACKGROUND: Dental agenesis is the most common, often heritable, developmental anomaly in humans. Although WNT10A gene mutations are known to cause rare syndromes associated with tooth agenesis, including onycho-odontodermal dysplasia (OODD), Schöpf ...
Huiying He, Dong Han, Hailan Feng, Hong Qu, Shujuan Song, Baojing Bai, Zhenting Zhang   +6 more
doaj   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature

BMC Oral Health, 2023
Background Progressive familial intrahepatic cholestasis is a heterogeneous group of disorders, leading to intrahepatic cholestasis, with the possibility of chronic liver failure and biliary cirrhosis.
Mina Yazdizadeh, Maryam Sharifi, Arefeh Torabi Parizi, Firoozeh Alipour, Maryam Ghasempuor, Elham Zanguei, Maryam Yazdizadeh   +6 more
doaj   +1 more source

Deep Phenotyping and Molecular Elucidation of a New Syndrome: Ectodermal Dysplasia Caused by IRF6 Variants

Experimental Dermatology, Volume 35, Issue 7, July 2026.
ABSTRACT The diagnosis of an ectodermal dysplasia (ED) is often made by dermatologists. Some of the more than 50 distinct ectodermal dysplasias, however, are still largely unknown and their pathogenesis is poorly understood. Since we recently discovered that variants of the Interferon Regulatory Factor 6 (IRF6) gene IRF6 may cause ED, we have further ...
Holm Schneider, Smail Hadj‐Rabia, Carola Berking, Matthias Weider, Julie Steffann, Ralf J. Rieker, Lina Gölz, Nicolai Peschel   +7 more
wiley   +1 more source

Isolated oligodontia in monozygotic twins

European Journal of Dentistry, 2013
ABSTRACTThis case report defines a case of isolated oligodontia of 9 and 10 permanent teeth in 9-year-old monozygotic twin sisters and gives information about the possible genetic and environmental etiology, related dental anomalies and treatment options.
HALICIOĞLU, KORAY, ŞAHİN, HAKAN, IRGIN, CELAL, TOPTAŞ, ORÇUN, ÇÖREKÇİ, BAYRAM   +4 more
openaire   +4 more sources

A Combination of Variants in SEPTIN9 and MSX1 Genes Leads to the Formation of Orofacial Clefts

Genes to Cells, Volume 31, Issue 4, July 2026.
Double‐depleted Xenopus embryos of xMSX1 and xSEPTIN9 exhibited orofacial clefts, and wild‐type but not variants in human MSX1 and human SEPTIN9 mRNAs could rescue the phenotype of morphants, indicating that variants in MSX1 and SEPTIN9, each individually tolerated, synergistically disrupt craniofacial morphogenesis to cause orofacial clefts.
Udval Uuganbayar, Zarko Manojlovic, Nao Ito, Reiko Yamaguchi, Hiromasa Ninomiya, Issei S. Shimada, Chisato Yamada, Devin Feigelson, Gretchen Schulz, Allyn Auslander, Sylvia Rakotoarison, William Magee III, Yutaka Hashimoto, Yoichi Kato   +13 more
wiley   +1 more source