Results 61 to 70 of about 2,549 (207)

A Combination of Variants in SEPTIN9 and MSX1 Genes Leads to the Formation of Orofacial Clefts

Genes to Cells, Volume 31, Issue 4, July 2026.
Double‐depleted Xenopus embryos of xMSX1 and xSEPTIN9 exhibited orofacial clefts, and wild‐type but not variants in human MSX1 and human SEPTIN9 mRNAs could rescue the phenotype of morphants, indicating that variants in MSX1 and SEPTIN9, each individually tolerated, synergistically disrupt craniofacial morphogenesis to cause orofacial clefts.
Udval Uuganbayar, Zarko Manojlovic, Nao Ito, Reiko Yamaguchi, Hiromasa Ninomiya, Issei S. Shimada, Chisato Yamada, Devin Feigelson, Gretchen Schulz, Allyn Auslander, Sylvia Rakotoarison, William Magee III, Yutaka Hashimoto, Yoichi Kato   +13 more
wiley   +1 more source

Isolated oligodontia in monozygotic twins

European Journal of Dentistry, 2013
ABSTRACTThis case report defines a case of isolated oligodontia of 9 and 10 permanent teeth in 9-year-old monozygotic twin sisters and gives information about the possible genetic and environmental etiology, related dental anomalies and treatment options.
HALICIOĞLU, KORAY, ŞAHİN, HAKAN, IRGIN, CELAL, TOPTAŞ, ORÇUN, ÇÖREKÇİ, BAYRAM   +4 more
openaire   +4 more sources

Evaluation of third molar agenesis associated with hypodontia and oligodontia in turkish pediatric patients

European Oral Research, 2020
Purpose To evaluate the association between third molar (M3) agenesis and hypodontia and oligodontia in pediatric patients by using panoramic radiography.Materials and Methods Panoramic radiographs of 1,471 patients (899 females; 572 males) and 5,884 ...
Meltem Tekbaş Atay, Neslihan Özveren, Gözde Serindere   +2 more
doaj   +1 more source

Familial Adenomatous Polyposis—Risk of Cancer, Cancer Prevention, and Long‐Term Consequences: Learnings from Five Decades with the Danish Polyposis Register

APMIS, Volume 134, Issue 5, May 2026.
ABSTRACT Familial adenomatous polyposis (FAP) is a hereditary condition marked by the growth of hundreds to thousands of adenomatous polyps in the colon and rectum, significantly elevating the risk of colorectal cancer (CRC) if left untreated. Caused by pathogenic variants in the APC gene, FAP is typically identified in adolescence, often leading to ...
John Gásdal Karstensen
wiley   +1 more source

Prosthetic Rehabilitation in Children: An Alternative Clinical Technique

Case Reports in Dentistry, 2013
Complete and partial removable dentures have been used successfully in numerous patients with oligodontia and/or anodontia. However, there is little information in the literature regarding the principles and guidelines to prosthetic rehabilitation for ...
Nádia Carolina Teixeira Marques, Carla Vecchione Gurgel, Ana Paula Fernandes, Marta Cunha Lima, Maria Aparecida Andrade Moreira Machado, Simone Soares, Thais Marchini Oliveira   +6 more
doaj   +1 more source

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 790-799, April 2026.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

Non syndromic Oligodontia: case report

, 2012
Oligodontia is a rare genetic disorder which represents the congenital absence of more than six teeth in primary, permanent or both dentitions. It is usually a part of a syndrome and seldom occurs as an isolated entity.
Tangade, Pradeep, Batra, Manu
core   +2 more sources

Early Oral Rehabilitation of a Pediatric Patient With Hypohidrotic Ectodermal Dysplasia: A Case Report from Afghanistan

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Hypohidrotic ectodermal dysplasia (HED) is a rare congenital disorder characterized by abnormal development of ectodermal structures including hair, teeth, nails, and sweat glands. Dental manifestations such as anodontia or hypodontia can significantly impair mastication, speech development, facial esthetics, and psychosocial well‐being ...
Nazera Ahmadzai, Hedayatullah Ehsan, Fatima Sapai, Mohammad Bashir Nejabi, Ahmad Anas Khairzad, Nematullah Sharifi   +5 more
wiley   +1 more source

Gastrointestinal symptoms in patients with isolated oligodontia and a Wnt gene mutation [PDF]

, 2023
OBJECTIVE: Since Wnt signaling plays an important role in both tooth agenesis and altered intestine homeostasis, the aim was to compare gastrointestinal symptoms in patients with isolated oligodontia caused by a Wnt pathway gene mutation and controls ...
Ross, Jamila N., van Nunen, Annick B, Ploos van Amstel, Hans Kristian, Rosenberg, Antoine J W P, Marco S. Cune, van Nunen, Annick B., Rosenberg, Antoine J.W.P., Créton, Marijn A., Créton, Marijn A, Jamila N. Ross, Ruigrok, Lisanne C, Hans‐Kristian Ploos van Amstel, Ross, Jamila N, Cune, Marco S, Ruigrok, Lisanne C., Annick B. van Nunen, Antoine J.W.P. Rosenberg, van den Boogaard, Marie-José J H, Marie‐José J.H. van den Boogaard, Ploos van Amstel, Hans-Kristian, Lisanne C. Ruigrok, Fennis, Willem M M, Fennis, Willem M.M., van den Boogaard, Marie José J.H., Marijn A. Créton, Cune, Marco S., Willem M.M. Fennis   +26 more
core   +1 more source

Prevalence and Patterns of Permanent Tooth Agenesis in Patients With Crouzon or Apert Syndrome: A Systematic Review and Meta‐Analysis

Orthodontics &Craniofacial Research, Volume 29, Issue 1, Page 1-11, February 2026.
ABSTRACT Crouzon and Apert syndromes are rare syndromic craniosynostoses frequently associated with craniofacial and dental anomalies, including tooth agenesis. Although individual studies have reported tooth agenesis prevalence data in specific populations, no attempts have been made to systematically synthesise these data.
M. Cecilia Becerril Santos, Edwin M. Ongkosuwito, Alexandra K. Papadopoulou, Gregory S. Antonarakis   +3 more
wiley   +1 more source