Results 111 to 120 of about 37,573 (244)
Experimental mechanisms that yield the growth of homochiral copolymers over their heterochiral counterparts have been advocated by Lahav and co-workers. These chiral amplification mechanisms proceed through racemic {\beta}-sheet-controlled polymerization
Blanco, Celia, Hochberg, David
core +1 more source
Antimicrobial and other oligopeptides of grapes
Structures and functions of about 700 oligopeptides of various plants are presently known. However, only one polypeptide has been isolated from grapes and characterized. At the same time, tens of thousands of uncharacterized amino acid sequences have been revealed in this plant, among which there can also be precursors of oligopeptide regulators.
Zamyatnin, A. A., Voronina, O. L.
openaire +4 more sources
In this study, a rational in silico strategy was employed to design a bioinsecticidal peptide targeting the digestive trypsins of Spodoptera frugiperda, utilizing the Dioscorin–trypsin interface as a structural template. By identifying critical interface hot‐spot residues, an 11‐residue oligopeptide designated as PEP‐11 was engineered, demonstrating ...
José Severiche‐Castro +2 more
wiley +1 more source
Evaluation of Structural Vulnerabilities in DNA Origami Nanoplatforms Using Ionizing Radiation
This study utilizes ionizing radiation to simulate long‐term degradation across three distinct DNA origami shapes, identifying structural weak points via AFM, AGE, and melting point analyses. Despite high radiation tolerance, exposed edges and single‐stranded domains show increased vulnerability, providing essential design benchmarks for engineering ...
Leo Sala +6 more
wiley +1 more source
Cyanobacterial toxins are a global threat to aquatic organisms; however, they represent only one group of bioactive cyanobacterial metabolites. Very little is known about the effects of other cyanobacterial products (e.g., non-ribosomal oligopeptides) on
Pawlik-Skowrońska Barbara +2 more
doaj +1 more source
Ab initio simulations of Cu binding sites in the N-terminal region of PrP [PDF]
The prion protein (PrP) binds Cu2+ ions in the octarepeat domain of the N-terminal tail up to full occupancy at pH=7.4. Recent experiments show that the HGGG octarepeat subdomain is responsible for holding the metal bound in a square planar coordination.
Furlan, S. +4 more
core +1 more source
Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz +13 more
wiley +1 more source
Oligopeptide sequences of the metal binding domain of CueR metalloregulatory proteins as candidates for toxic metal ion capture [PDF]
Various toxic metal ion resistance systems operate from bacterial level up to higher plants and animals. In bacteria, metalloregulatory proteins are key factors in the control of metal ion level.
Gyurcsik, Béla +2 more
core +2 more sources
In Silico Approach towards Designing Virtual Oligopeptides for HRSV
HRSV (human respiratory syncytial virus) is a serious cause of lower respiratory tract illness in infants and young children. Designing inhibitors from the proteins involved in virus replication and infection process provides target for new therapeutic ...
Ruchi Jain, Shanmughavel Piramanayagam
doaj +1 more source
Conjugated 2′‐Fucosyllactose–Potato Protein Hydrolysate as Novel Prebiotics
This study introduces a novel protein‐containing prebiotic based on 2′‐FL‐PPH Maillard conjugates micelles that co‐deliver proteins and carbohydrates to the colon to selectively nourish colonic probiotics. These digestion‐resistant micelles enhanced Bifidobacteria, SCFAs, gut barrier integrity, and metabolic health more effectively than conventional ...
Stav Peled +4 more
wiley +1 more source

