Results 201 to 210 of about 37,573 (244)

Oligopeptide cyclophilin inhibitors: A reassessment

European Journal of Medicinal Chemistry, 2011
Potent cyclophilin A (CypA) inhibitors such as non-immunosuppressive cyclosporin A (CsA) derivatives have been already used in clinical trials in patients with viral infections. CypA is a peptidyl prolyl cis/trans isomerase (PPIase) that catalyzes slow prolyl bond cis/trans interconversions of the backbone of substrate peptides and proteins.
Michael, Schumann, Günther, Jahreis, Viktoria, Kahlert, Christian, Lücke, Gunter, Fischer   +4 more
openaire   +2 more sources

Thermolysin: Kinetic Study with Oligopeptides

European Journal of Biochemistry, 1970
Thermolysin is a well‐known protease which exhibits its specificity against hydrophobic amino acid residues such as l‐leucine, l‐phenylalanine, etc. whose amino groups donate the susceptible peptide bonds (amino‐endopeptidase). The present study was undertaken to investigate the effects of neighboring residues surrounding the sensitive amino acid ...
K, Morihara, H, Tsuzuki
openaire   +2 more sources

Intestinal Absorption of Oligopeptides in Cystinuria

Clinical Science, 1971
1. The intestinal transport of oligopeptides containing either lysine or arginine has been compared with that of the corresponding free amino acids in six homozygous cystinuric patients and in six normal adult subjects by use of the oral tolerance test technique. 2.
A M, Asatoor, M R, Crouchman, A R, Harrison, F W, Light, L W, Loughridge, M D, Milne, A J, Richards   +6 more
openaire   +2 more sources

Self-Assembly of Homo Phenylalanine Oligopeptides: Role of Oligopeptide Chain Length

Langmuir
The self-assembly of phenylalanine (F)-based peptides is a critical area of research with potential implications for the development of advanced biomaterials and technologies. Previous studies indicate that homo-oligopeptides with F-X residues (X = 1 to 6) can self-assemble into diverse nano-microstructures, but the role of oligopeptide chain length on
Safaa Kader, Muntadher Sultan, Esmaiel Jabbari   +2 more
openaire   +2 more sources

Metal ion selectivity of oligopeptides

Dalton Trans., 2006
Metal binding affinity and selectivity of peptides are reviewed with a special emphasis on the high structural variety of peptide complexes. The most common structural type of these complexes is built up by the deprotonation and metal ion coordination of subsequent amide groups in the form of fused five-membered chelate rings. The metal ion selectivity
Imre, Sóvágó, Katalin, Osz
openaire   +2 more sources

Oligopeptides in the formation of biological motivations

Neuroscience and Behavioral Physiology, 1987
1. Oligopeptides participate in the organization of eating and defense behavior and self-stimulation. 2. The majority of the investigated oligopeptides when injected into the lateral ventricles have an inhibitory influence on the manifestation of biological motivations.
openaire   +2 more sources

Conformational Preferences of Proline Oligopeptides

The Journal of Physical Chemistry B, 2006
A conformational study on the terminally blocked proline oligopeptides, Ac-(Pro)(n)()-NMe(2) (n = 2-5), is carried out using the ab initio Hartree-Fock level of theory with the self-consistent reaction field method in the gas phase and in solutions (chloroform, 1-propanol, and water) to explore the preference and transition between polyproline II (PPII)
Young Kee, Kang, Jong Suk, Jhon, Hae Sook, Park   +2 more
openaire   +2 more sources

Interactions of Oligopeptides With Nucleic Acid

Critical Reviews in Biochemistry, 1981
(1981). Interactions of Oligopeptides With Nucleic Acid. Critical Reviews in Biochemistry: Vol. 10, No. 3, pp. 213-258.
Claude Helene, Jean-Claude Maurizot, Karl G. Wagner   +2 more
openaire   +2 more sources

Bacterial oligopeptide-binding proteins

Cellular and Molecular Life Sciences (CMLS), 2003
This review focuses on bacterial oligopeptide-binding proteins, which form part of the oligopeptide transport system belonging to the ATP-binding cassette family of transporters. Depending on the bacterial species, these binding proteins (OppA) capture peptides ranging in size from 2 to 18 amino acids from the environment and pass them on to the other ...
openaire   +2 more sources

Vibrational optical activity of oligopeptides

Biopolymers, 1995
AbstractVibrational optical activity (VOA) is a relatively newspectroscopic technique, which has two principal manifestations, ir vibrational CD and vibrational Raman optical activity. Progress in the study of oligopeptides using both of these forms of VOA is reviewed from the perspective of theoretical and instrumental techniques, spectral results ...
T B, Freedman, L A, Nafie, T A, Keiderling   +2 more
openaire   +2 more sources