Results 251 to 260 of about 458,280 (341)

Beyond Single Chains: Benchmarking Macromolecular Complex Prediction Methods With the Continuous Automated Model EvaluatiOn (CAMEO)

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Independent, blind assessment of structure prediction methods is essential for establishing state‐of‐the‐art performance, identifying limitations, and guiding future developments. The Continuous Automated Model EvaluatiOn (CAMEO) platform provides weekly, automated benchmarking of structure prediction servers, complementing the biennial ...
Xavier Robin   +6 more
wiley   +1 more source

In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini   +5 more
wiley   +1 more source

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza   +3 more
wiley   +1 more source

Dietary Mannan Oligosaccharides Enhance Lactational Performance, Nutrient Metabolism, Plasma Metabolomics, and Gut Microbiota in Dezhou Donkeys. [PDF]

open access: yesInt J Mol Sci
Wang T   +13 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy