Results 271 to 280 of about 458,280 (341)

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

open access: yesSmall Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang   +9 more
wiley   +1 more source

Release of oligosaccharides from various glycosphingolipids by endo-beta-galactosidase.

open access: hybrid, 1978
Michiko N. Fukuda   +2 more
openalex   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

open access: yesSmall Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz   +5 more
wiley   +1 more source

Cell‐Free Protein Crystallization Enables Rapid Structure Determination of Disaccharides and Trisaccharides Using Galectin‐10 Crystals

open access: yesSmall Structures, EarlyView.
Galectin‐10 crystals prepared by cell‐free protein crystallization serve as the scaffold to capture the saccharides to determine the atomic‐resolution structure of a trisaccharide bound to protein. Molecular dynamics simulation combined with the mutation of scaffold crystals offers insights into how the binding site architecture modulates saccharide ...
Mariko Kojima   +7 more
wiley   +1 more source

Optimizing (Bio) Catalysis with Liquid‐Liquid Phase Separation Systems

open access: yesChemSystemsChem, EarlyView.
This review highlights how LLPS creates membraneless compartments involved in different scenarios in nature. It further explores different examples that focus on the development of synthetic coacervates that enhance catalytic efficiency by concentrating reactants, or by the direct influence of the coacervates building blocks themselves.
David Q. P. Reis   +4 more
wiley   +1 more source

European Consensus on Functional Bloating and Abdominal Distension—An ESNM/UEG Recommendations for Clinical Management

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Abdominal distension is an objective visible sign of increased abdominal girth. Bloating is a feeling of abdominal fullness and discomfort. Bloating may be associated or not with abdominal distension. Bloating and abdominal distension are among the most commonly reported gastrointestinal symptoms and may be associated with both ...
Chloé Melchior   +20 more
wiley   +1 more source

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