Results 1 to 10 of about 391,627 (127)

Migration study of phthalates from non-food plastic containers used in food preservation [PDF]

open access: yesHeliyon, 2023
Phthalate acid esters (PAE) are used as additives in the formulation of plastics, to increase their flexibility and transparency. They can migrate from plastic packaging to food, then cause endocrine disruption in consumers. This migration depends on the
Olivier Songue Same   +6 more
doaj   +3 more sources

Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes [PDF]

open access: yesiScience, 2023
Summary: Metformin (MET) is the most prescribed antidiabetic drug, but its mechanisms of action remain elusive. Recent data point to the gut as MET’s primary target. Here, we explored the effect of MET on the gut glucose transport machinery.
Lorea Zubiaga   +26 more
doaj   +3 more sources

The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection [PDF]

open access: yesFrontiers in Immunology, 2023
Purinergic receptors and NOD-like receptor protein 3 (NLRP3) inflammasome regulate inflammation and viral infection, but their effects on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain poorly understood.
Déborah Lécuyer   +58 more
doaj   +4 more sources

Inhibition of HIV-1 replication by primer RNA packaging inhibitors [PDF]

open access: yesmBio
An essential step in the life cycle of human immunodeficiency virus type 1 (HIV-1) is the packaging of tRNA3Lys during viral assembly. This step, which requires the assembly of a ternary complex consisting of GagPol, mitochondrial lysyl-tRNA synthetase ...
Marc Mirande   +4 more
doaj   +3 more sources

Different Pathways Leading to Integrase Inhibitors Resistance. [PDF]

open access: yesFront Microbiol, 2016
Integrase strand-transfer inhibitors (INSTIs), such as raltegravir (RAL), elvitegravir, or dolutegravir (DTG), are efficient antiretroviral agents used in HIV treatment in order to inhibit retroviral integration.
Thierry E, Deprez E, Delelis O.
europepmc   +3 more sources

Integrase and integration: biochemical activities of HIV-1 integrase [PDF]

open access: yesRetrovirology, 2008
Integration of retroviral DNA is an obligatory step of retrovirus replication because proviral DNA is the template for productive infection. Integrase, a retroviral enzyme, catalyses integration.
Deprez Eric   +4 more
doaj   +3 more sources

CDC20B is required for deuterosome-mediated centriole production in multiciliated cells [PDF]

open access: yesNature Communications, 2018
In vertebrate multiciliated cells, most centrioles are synthesized and released by poorly characterized structures called deuterosomes. Here, the authors report that the previously-uncharacterized Cdc20b in mouse and Xenopus associates with deuterosomes ...
Diego R. Revinski   +14 more
doaj   +3 more sources

Interplay between Intrinsic and Innate Immunity during HIV Infection [PDF]

open access: yesCells, 2019
Restriction factors are antiviral components of intrinsic immunity which constitute a first line of defense by blocking different steps of the human immunodeficiency virus (HIV) replication cycle.
Louis Bergantz   +4 more
doaj   +3 more sources

Olivier Deprez et les frontières de la bande dessinée

open access: yesRelief: Revue Électronique de Littérature Francaise, 2008
La bande dessinée contemporaine est le résultat de trois révolutions : celle du contenu, qui n’est plus confiné à l’humour ; celle ensuite de son support, qui est devenu le livre ; celle enfin de ses techniques, qui ne se réduisent plus au dessin colorié.
Jan Baetens
doaj   +6 more sources

L’ENTERREMENT DE KASIMIR MALEVITCH

open access: yesRelief: Revue Électronique de Littérature Francaise, 2008
Cette variation sur Malevitch trouve son origine dans la lithographie de l'artiste russe intitulée "Troïé". Sur cette lithographie, on distingue un personnage surmontant une virgule, tournant le dos au spectateur et s'enfonçant dans le blanc de la page ...
Olivier Deprez
doaj   +6 more sources

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