Results 51 to 60 of about 17,255 (225)

Peptide Marriages: Modular Assembly of Multi‐Agonist Therapeutics

Chemistry – A European Journal, EarlyView.
A modular polyethylene glycol (PEG) scaffold enables rapid assembly of dual peptide agonists using strain‐promoted azide–alkyne cycloaddition (SPAAC) and copper‐catalysed azide–alkyne cycloaddition (CuAAC). Glucagon‐like peptide‐1 (GLP‐1) and amylin agonists were combined with controlled valency, yielding low‐picomolar activity and receptor‐selective ...
Kristina A. Kostadinova, Jan L. Venne, Sona Krajcovicova, James Dodgson, Wouter F. J. Hogendorf, Thomas E. Nielsen, David Hymel, Hannah Bolt, Andie Collinson, Jason Day, Jefferson Revell, David R. Spring   +11 more
wiley   +1 more source

Humanists in Olomouc in the Late Fifteenth and First Half of the Sixteenth Century and Their Influence on Progressive Early Renaissance Architectural Sculpture in Moravia

Mesto a dejiny
This article focuses on the relationship between the Olomouc humanists and the progressive early Renaissance architectural sculpture on the buildings they commissioned in Moravia in the first half of the sixteenth century.
Petr Čehovský
semanticscholar   +1 more source

Raman Optical Activity as a Tool to Monitor Polynucleotide Conformation in Solutions

Chemistry – A European Journal, EarlyView.
Raman optical activity (ROA) studies of nucleic acids have been hindered by limited computational tools to link the spectra to the structure. The study shows that accurate density functional simulations are possible for model nucleotides, bringing more information about molecular geometry and dynamics in solutions.
Mohammed Siddhique Para Kkadan, Josef Kapitán, Jiří Kessler, Ondřej Zapletal, Valery Andrushchenko, Petr Bouř   +5 more
wiley   +1 more source

Homework in Cognitive Behavioral Supervision: Theoretical Background and Clinical Application

Psychology Research and Behavior Management, 2022
Jan Prasko,1– 4 Ilona Krone,5 Julius Burkauskas,6 Jakub Vanek,1 Marija Abeltina,7 Alicja Juskiene,6 Tomas Sollar,2 Ieva Bite,7 Milos Slepecky,2 Marie Ociskova1,4 1Department of Psychiatry, University Hospital Olomouc, Faculty of Medicine, Palacky ...
Prasko J, Krone I, Burkauskas J, Vanek J, Abeltina M, Juskiene A, Sollar T, Bite I, Slepecky M, Ociskova M   +9 more
doaj  

Defining Reconciliation Studies: Theoretical and Practical Dimensions

Conflict Resolution Quarterly, EarlyView.
ABSTRACT Reconciliation studies (RS) has become increasingly influential in understanding alternative views to ending conflict and dealing with the aftermath. As a discipline or field, however, it is not well defined. The actual usefulness of reconciliation (as a concept), or of RS (as a discipline), is debated, and due to its growing usage, it is ...
Colleen Alena O’Brien
wiley   +1 more source

Sleep Disturbances in Patients with Nonepileptic Seizures

Nature and Science of Sleep, 2021
Jakub Vanek,1 Jan Prasko,1– 3 Marie Ociskova,1 Samuel Genzor,4 Michaela Holubova,5 Frantisek Hodny,1 Vlastmil Nesnidal,1 Milos Slepecky,3 Milan Sova,4 Kamila Minarikova1 1Department of Psychiatry, Faculty of Medicine and Dentistry, University ...
Vanek J, Prasko J, Ociskova M, Genzor S, Holubova M, Hodny F, Nesnidal V, Slepecky M, Sova M, Minarikova K   +9 more
doaj  

Calibration‐Free Single‐Frame Super‐Resolution Fluorescence Microscopy

Laser &Photonics Reviews, EarlyView.
A deep learning framework reconstructs super‐resolved fluorescence images from a single dense camera frame, without any prior calibration or knowledge of the microscope. Trained solely on synthetic data, it generalizes across imaging setups and conditions.
Anežka Dostálová, Dominik Vašinka, Robert Stárek, Miroslav Ježek   +3 more
wiley   +1 more source

Target‐site mutations and phenotypic failure in Myzus persicae against pyrethroids and carbamates in central Europe

Pest Management Science, EarlyView.
Molecular screening of 140 field‐collected Myzus persicae aphids revealed target‐site mutations L1014F, M918L, M918T, and L932F in the sodium channel and S431F in Ace2. The M918L mutation was the primary driver of high pyrethroid (cypermethrin) resistance, while S431F served as a definitive marker for carbamate (pirimicarb) resistance.
Jitka Stara, Jan Hubert, Pavla Pabiskova, Frantisek Kocourek   +3 more
wiley   +1 more source

Perception of future teachers professional competences level at Faculty of Science, Palacký University Olomouc

Paidagogos, 2022
The paper aims to identify and propose possible solutions in the case of perception of the level of professional competencies of first-year students of the follow-up study of teaching at the Faculty of Science, Palacký University Olomouc, from the ...
Jana Slezáková
doaj  

Laser‐Assisted In Situ Fabrication of rGO/Bi2O3 Nanocomposites for Heavy Metal Sensing

Small, EarlyView.
Rapid CO2 laser irradiation drives the in situ formation of Bi2O3 nanoplatelets within reduced graphene oxide, yielding flexible, reproducible electrodes with excellent stripping voltammetric performance toward trace heavy metals. ABSTRACT In this work, we introduce a laser‐assisted approach to synthesize reduced graphene oxide/bismuth oxide (III) (rGO/
Andy Bruno, Ana Ameda, Ivan Dědek, Majlinda Vasjari, Michal Otyepka, Ruslán Alvarez‐Diduk, Arben Merkoçi   +6 more
wiley   +1 more source