Cellular Physiology and Biochemistry, 2015 Backgroud/Aims: Besides its anti-allergic properties as a histamine receptor antagonist, olopatadine stabilizes mast cells by inhibiting the release of chemokines.
Itsuro Kazama +2 more
exaly +4 more sources
Olopatadine Exerts Multifaceted Protective Effects in an Ovalbumin-Induced Allergic Eye Disease Mouse Model [PDF]
BioengineeringAllergic eye disease (AED), including allergic conjunctivitis, is a prevalent immune-mediated disorder of the ocular surface characterized by itching, redness, tearing, and ocular discomfort.
Basanta Bhujel +5 more
doaj +2 more sources
Comprehensive Analytical Investigation of the Photodegradation of Olopatadine and In Silico Toxicity Assessment of Its Photodegradation Products [PDF]
MoleculesOlopatadine (OLO) is a second-generation antihistamine approved for the treatment of allergic conjunctivitis as ophthalmic and nasal solutions. Due to its intrinsic absorption in the near-UV region (approximately 300 nm), OLO may be susceptible to ...
Anna Gumieniczek +4 more
doaj +2 more sources
Advances in the management of allergic rhinitis: clinical relevance of the mometasone furoate–olopatadine association and the challenge of patient self-diagnosis and self-treatment [PDF]
Drugs in ContextAllergic rhinitis is a highly prevalent inflammatory disease that significantly impairs sleep, daily functioning and quality of life, with symptoms increasingly amplified by environmental changes such as prolonged pollen seasons and urban pollution ...
Maria D’Amato, Gennaro D’Amato
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Second-generation H1 antihistamines for the treatment of chronic urticaria: a network meta-analysis [PDF]
Frontiers in MedicineObjectiveTo evaluate the efficacy and safety of 10 commonly used second-generation H1 antihistamines (cetirizine, levocetirizine, loratadine, desloratadine, ebastine, bilastine, olopatadine, rupatadine, fexofenadine, and mizolastine) at licensed doses in
Zixuan Li +26 more
doaj +2 more sources
Olopatadine plus mometasone for seasonal allergic rhinitis treatment: A pooled analysis of clinical trials [PDF]
Brazilian Journal of OtorhinolaryngologyObjective: This study was conducted to analyze the efficacy and safety of a fixed-dose combination of olopatadine HCl (antihistamine) and mometasone furoate (corticosteroid) (Olo/Mom, GSP301) for the treatment of Seasonal Allergic Rhinitis (SAR). Methods:
Marcio Nakanishi +6 more
doaj +2 more sources
Comparative Effects of Anti-Inflammatory Therapies on Olfactory Bulb Histopathology and Olfactory Function in a Rat Model of Experimental Allergic Rhinitis [PDF]
Journal of Inflammation ResearchEngin Kayıkçı,1 Hazal Kayıkçı2 1Ministry of Health, Etlik City Hospital, Department of Neurosurgery, Ankara, Turkiye; 2Division of Allergy and Clinical Immunology, Hacettepe University, Ankara ...
Kayıkçı E, Kayıkçı H
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Pharmacology and Clinical Pharmacy Research, 2022 The study aimed to compare the cost-effectiveness and safety of 0.2% Olopatadine with a combination of 0.1% Olopatadine and 0.4% Ketorolac eye drops in Vernal keratoconjunctivitis (VKC) among the rural population.
Adhiti Todime +5 more
doaj +1 more source
Olopatadine Hydrochloride and Fluticasone Propionate in Topical Treatment of Allergic Rhinitis: A Single Blind Randomised Study [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: The use of corticosteroids or antihistaminics in treatment of allergic rhinitis is known and practiced since long. The efficacy of topical use of fluticasone propionate and Olopatadine Hydrochloride (HCL) for symptomatic relief of ...
Abhay Havle +6 more
doaj +1 more source
Indian Journal of Ophthalmology, 2021 Purpose: To compare the efficacy and safety of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2%, and Bepotastine besilate 1.5% ophthalmic solutions in the treatment of allergic conjunctivitis. Methods: This is a prospective, observer-masked, comparative
Shruti Ayyappanavar +7 more
doaj +1 more source