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Comprehensive Analytical Investigation of the Photodegradation of Olopatadine and In Silico Toxicity Assessment of Its Photodegradation Products [PDF]

open access: yesMolecules
Olopatadine (OLO) is a second-generation antihistamine approved for the treatment of allergic conjunctivitis as ophthalmic and nasal solutions. Due to its intrinsic absorption in the near-UV region (approximately 300 nm), OLO may be susceptible to ...
Anna Gumieniczek   +4 more
doaj   +2 more sources

Advances in the management of allergic rhinitis: clinical relevance of the mometasone furoate–olopatadine association and the challenge of patient self-diagnosis and self-treatment [PDF]

open access: yesDrugs in Context
Allergic rhinitis is a highly prevalent inflammatory disease that significantly impairs sleep, daily functioning and quality of life, with symptoms increasingly amplified by environmental changes such as prolonged pollen seasons and urban pollution ...
Maria D’Amato, Gennaro D’Amato
doaj   +2 more sources

Second-generation H1 antihistamines for the treatment of chronic urticaria: a network meta-analysis [PDF]

open access: yesFrontiers in Medicine
ObjectiveTo evaluate the efficacy and safety of 10 commonly used second-generation H1 antihistamines (cetirizine, levocetirizine, loratadine, desloratadine, ebastine, bilastine, olopatadine, rupatadine, fexofenadine, and mizolastine) at licensed doses in
Zixuan Li   +26 more
doaj   +2 more sources

Olopatadine plus mometasone for seasonal allergic rhinitis treatment: A pooled analysis of clinical trials [PDF]

open access: yesBrazilian Journal of Otorhinolaryngology
Objective: This study was conducted to analyze the efficacy and safety of a fixed-dose combination of olopatadine HCl (antihistamine) and mometasone furoate (corticosteroid) (Olo/Mom, GSP301) for the treatment of Seasonal Allergic Rhinitis (SAR). Methods:
Marcio Nakanishi   +6 more
doaj   +2 more sources

Comparative Effects of Anti-Inflammatory Therapies on Olfactory Bulb Histopathology and Olfactory Function in a Rat Model of Experimental Allergic Rhinitis [PDF]

open access: yesJournal of Inflammation Research
Engin Kayıkçı,1 Hazal Kayıkçı2 1Ministry of Health, Etlik City Hospital, Department of Neurosurgery, Ankara, Turkiye; 2Division of Allergy and Clinical Immunology, Hacettepe University, Ankara ...
Kayıkçı E, Kayıkçı H
doaj   +2 more sources

Study of Cost-effectiveness and Safety of 0.2% Olopatadine in Comparison with Combination of 0.1% Olopatadine and 0.4% Ketorolac Eye Drops in Vernal Keratoconjunctivitis among Rural Population

open access: yesPharmacology and Clinical Pharmacy Research, 2022
The study aimed to compare the cost-effectiveness and safety of 0.2% Olopatadine with a combination of 0.1% Olopatadine and 0.4% Ketorolac eye drops in Vernal keratoconjunctivitis (VKC) among the rural population.
Adhiti Todime   +5 more
doaj   +1 more source

Olopatadine Hydrochloride and Fluticasone Propionate in Topical Treatment of Allergic Rhinitis: A Single Blind Randomised Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The use of corticosteroids or antihistaminics in treatment of allergic rhinitis is known and practiced since long. The efficacy of topical use of fluticasone propionate and Olopatadine Hydrochloride (HCL) for symptomatic relief of ...
Abhay Havle   +6 more
doaj   +1 more source

Comparative analysis of safety and efficacy of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2% and Bepotastine besilate 1.5% in allergic conjunctivitis

open access: yesIndian Journal of Ophthalmology, 2021
Purpose: To compare the efficacy and safety of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2%, and Bepotastine besilate 1.5% ophthalmic solutions in the treatment of allergic conjunctivitis. Methods: This is a prospective, observer-masked, comparative
Shruti Ayyappanavar   +7 more
doaj   +1 more source

Topical ketotifen treatment for allergic conjunctivitis: a systematic review and Meta-analysis [PDF]

open access: yesInternational Journal of Ophthalmology, 2023
AIM: To assess the efficacy of ketotifen in treating allergic conjunctivitis. METHODS: A systematic search of systematic reviews and Meta-analyses was conducted on the PubMed and Web Science of Science until October 2021 to address this knowledge gap ...
Xin-Yan Dou, Wei Zhang
doaj   +1 more source

Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

open access: yesMediators of Inflammation, 2006
Olopatadine hydrochloride (olopatadine) is an antiallergic drug with histamine H1 receptor antagonistic activity. Recently, olopatadine has been shown to bind to S100A12 which is a member of the S100 family of calcium-binding proteins, and exerts ...
Kazuya Kishimoto   +4 more
doaj   +2 more sources

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