Results 141 to 150 of about 1,510 (191)
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Azelastine and olopatadine in the treatment of allergic rhinitis
Annals of Allergy, Asthma & Immunology, 2009To review the literature supporting current recommendations for nasal antihistamines as first-line therapy for allergic rhinitis.Published articles in the peer-reviewed medical literature.Clinical trials focusing on the efficacy, safety, and recommended uses of the currently approved nasal antihistamines in the United States: azelastine nasal spray, 0 ...
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Olopatadine nasal spray for the treatment of allergic rhinitis
Expert Review of Clinical Immunology, 2010Olopatadine hydrochloride nasal spray (Patanase Nasal Spray, Alcon Laboratories, TX, USA) was approved by the US FDA in 2008, and is indicated for the relief of symptoms of seasonal allergic rhinitis (SAR), also referred to as allergic rhinosinusitis. Olopatadine is an antihistamine with selective H1-receptor antagonist activity.
Peter S, Roland +2 more
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Safety and Tolerability of Olopatadine 0.2% in Children and Adolescents
Journal of Ocular Pharmacology and Therapeutics, 2007The aim of this study was to evaluate the safety of olopatadine hydrochloride ophthalmic solution 0.2% in children and adolescents 3-17 years of age.In this 6-week, randomized, double-masked safety evaluation, eligible subjects with asymptomatic eyes underwent in-office visits at weeks 1, 3, and 6 and were contacted by telephone at weeks 2, 4, and 5 ...
Steven J, Lichtenstein +5 more
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Effects of olopatadine in limited scleroderma with peripheral eosinophils
Geriatrics & Gerontology International, 2008Scleroderma and eosinophilia often occur together, though the pathogenesis is unclear. We investigated the effect of olopatadine hydrochloride in a series of cases of limited scleroderma (LS). Ten patients with LS and positive eosinophil counts (LSE) were enrolled (average age, 85 years; six men and four women).
Motoo, Kikuchi +4 more
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Pharmacology, clinical efficacy and safety of olopatadine hydrochloride
Expert Review of Clinical Immunology, 2006Olopatadine is a multimechanism anti-allergic agent that inhibits H(1) receptor activation and stabilizes mast cell membranes, blocking the release of allergic and inflammatory mediators. Studies in human conjunctival mast cells clearly demonstrate, in the relevant tissue and species, olopatadine's inhibition of histamine release, which was ...
Steven J, Lichtenstein, Mark B, Abelson
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ACID BASE EQUILIBRIA OF OLOPATADINE IN AQUEOUS MEDIA
Physical Chemistry 2024 : proceedings Vol. 2The pKa values of olopatadine were potentiometrically determined in the presence and in the absence of differently charged micelles, anionic, cationic and nonionic. The ionization of olopatadine has been significantly affected by the interactions of ionizable groups with micelles (∆pKa -2.21 to +2.75).
Marija Popović-Nikolić +2 more
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