Results 31 to 40 of about 28,422 (269)
LINX®, a novel treatment for patients with refractory asthma complicated by gastroesophageal reflux disease: a case report. [PDF]
, 2016 BackgroundGastroesophageal reflux disease is one of the most common comorbidities in patients with asthma. Gastroesophageal reflux disease can be linked to difficult-to-control asthma.
Kenyon, Nicholas J +6 more
core +2 more sources
Journal of Personalized Medicine, 2023 Background: Insufficient data are available on the long-term “real-life” safety profile of omalizumab in children. This study evaluated the long-term safety of omalizumab in a pediatric cohort with severe asthma or chronic spontaneous urticaria (CSU ...
F. Galletta +8 more
semanticscholar +1 more source
The World Allergy Organization Journal, 2023 Immunoglobulin E (IgE) plays a critical role in the allergen-initiated inflammatory pathway and thus serves as a viable therapeutic target in allergic or IgE-mediated diseases such as asthma.
Francesco Menzella +7 more
semanticscholar +1 more source
Development of Assay for Determining Free IgE Levels in Serum from Patients Treated with Omalizumab
Allergology International, 2014 Background: Omalizumab, a monoclonal anti-IgE antibody, is currently indicated for the treatment of moderate-to-severe allergic asthma. To measure active IgE levels in sera from patients treated with omalizumab, the IgE subfraction in complex with ...
Reiko Ito +9 more
doaj +1 more source
Efficacy and safety of omalizumab against chronic spontaneous urticaria: Real-world study from China
World Allergy Organization Journal, 2022 Background: Omalizumab is an effective treatment for chronic spontaneous urticaria (CSU) patients aged ≥12 years, but its efficacy in patients aged
Ao Wang, MD +7 more
doaj +1 more source
Recovery of smell sense loss by mepolizumab in a patient allergic to dermatophagoides and affected by chronic rhinosinusitis with nasal polyps [PDF]
, 2019 Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently presents with dysfunction or loss of the sense of smell, resulting in a signifcant impairment in quality of life.
Cavaliere, Carlo +7 more
core +1 more source
Real-Life Effects of Omalizumab on Chronic Rhinosinusitis with Nasal Polyposis
Journal of Personalized Medicine, 2023 Chronic rhinosinusitis with nasal polyposis (CRSwNP) is an inflammatory disease of the nasal and sinus mucosa. This inflammatory process is supported by a multitude of cytokines, including IL-4, IL-5, and IL-13 produced by Th2 cells, as well as by IgE ...
N. Lombardo +8 more
semanticscholar +1 more source
The future outlook on allergen immunotherapy in children: 2018 and beyond. [PDF]
, 2018 Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases.
Arasi S, Corsello G, Pajno GB, Villani A
core +2 more sources
Annals of Allergy, Asthma & Immunology, 2023 BACKGROUND Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) often have atopic comorbidities, including elevated immunoglobulin E (IgE) levels and comorbid asthma. Omalizumab, an IgE monoclonal antibody, is an effective treatment for CRSwNP,
P. Gevaert +6 more
semanticscholar +1 more source
Prototype of running clinical trials in an untrustworthy environment using blockchain. [PDF]
, 2019 Monitoring and ensuring the integrity of data within the clinical trial process is currently not always feasible with the current research system.
Bhattacharya, Sanchita +2 more
core +3 more sources