Results 201 to 210 of about 77,402 (300)

SARS-CoV-2 Delta variant-specific ORF3a mutations destabilize lysosomal homeostasis to trigger lysosomal damage-mediated cell death. [PDF]

Commun Biol
Dey AA, Mishra S, Ashireddygari VR, Vemparala B, Chandra A, Jain D, Dixit NM, Tammineni P, Kesavardhana S.   +8 more
europepmc   +1 more source

Neutralization susceptibility of Omicron lineages

Nature Reviews Immunology, 2022
openaire   +2 more sources

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection. [PDF]

Nat Commun
Vu MN, Alvarado RE, Morris DR, Lokugamage KG, Zhou Y, Morgan AL, Ahearn YP, Hazell NC, Estes LK, McLeland AM, Schindewolf C, Plante JA, Meyers WM, Murray JT, Crocquet-Valdes PA, Weaver SC, Suthar MS, Walker DH, Russell WK, Routh AL, Hu H, Plante KS, Menachery VD.   +22 more
europepmc   +1 more source

Partial Phase‐Separation in the Initial Growth Stage of Exsolution‐Active SrTi0.95‐xNi0.05NbxO3‐δ Thin Films

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Phase separation emerges during the initial growth of heavily Ni‐ and Ni,Nb‐co‐doped STO thin films, leading to preferential accumulation of Ni and embedded NiOx nanoinclusions in thicker films. Nb co‐doping partially suppresses the ordering of these embedded structures, comprising about 20% of all Ni ions.
Yen‐Po Liu, Moritz L. Weber, Dylan Jennings, Leonid L. Rusevich, Eugene Kotomin, Rainer Timm, Felix Gunkel, Regina Dittmann   +7 more
wiley   +1 more source

Quantitative analysis of massive SARS-CoV-2 testing in the community in France in 2021-2022 reveals the associations of variant, vaccination, and age with viral dynamics in symptomatic individuals. [PDF]

PLoS Comput Biol
Beaulieu M, Hozé N, Vieillefond V, Goetschy T, Cosentino G, Blanquart F, Débarre F, Guedj J.   +7 more
europepmc   +1 more source

Higher SARS-CoV-2 infection burden among racialized individuals: evidence from Canadian serology data. [PDF]

BMC Public Health
Mann S, Wilson N, Lee C, Fisman DN.
europepmc   +1 more source

Prophylaxis Strategies for SARS‐CoV‐2 Infection in Adults With Hematological Malignancies in Saudi Arabia: Consensus Statements From the Working Group on COVID‐19 Management in Hematological Malignancies

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Despite the end of the pandemic phase, patients with hematological malignancies (HMs) remain vulnerable to severe COVID‐19 infection and mortality. Prophylaxis strategies, including vaccination and monoclonal antibodies (mAbs) like AZD7442, are crucial for protection.
Mubarak Al‐Mansour, Ayman Alhejazi, Manal Ahmed Alsaggaf, Hafiz Mosa Malhan, Riad El Fakih, Reyad Dada, Ghazi Saud Alotaibi, Reem S. Almaghrabi, Majid Alshamrani   +8 more
wiley   +1 more source

Omicron respiratory threat in renal transplant recipients. [PDF]

Caspian J Intern Med
Akbari R, Abolghasemi S, Shafiekhani M, Asgharpour M, Zare Z, Nikoupour H, Roozbeh J, Mahmoudi Chalmiani E, Oliaie F, Baziboroun M, Nezami S.   +10 more
europepmc   +1 more source

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults

Clinical Pharmacology in Drug Development, Volume 15, Issue 10, October 2026.
Abstract REGN17092, a fully human immunoglobulin (Ig) G1 antibody with M252Y/S254T/T256E (YTE) modification in the Fc portion, was assessed in a first‐in‐human study (ClinicalTrials.gov, NCT05923424). REGN17092 was designed to target the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) S protein.
Maria Rosario, Jan de Hoon, Flonza Isa, Kenneth Turner, Jing Li, Joel Kantrowitz, Samit Ganguly, Sasha Fraser, Zhongqing Will He, Hong Yan, Ana Gonzalez Ortiz, Lori Faria, Ingeborg Heirman, Alina Baum, Thomas D Norton, Yogesh Patel, Veronica Mas Casullo, John D Davis   +17 more
wiley   +1 more source