Results 61 to 70 of about 77,402 (300)

CarloFischer88/Gradual-emergence-followed-by-exponential-spread-of-the-SARS-CoV-2-Omicron-variant-in-Africa-V-1.4: Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in Africa

, 2022
Scipts and GISIAD references for Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in ...
Carlo Fischer
core   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Site Density Governs Switching Reactivity Regimes During Aerobic C─H Oxidation in Mn Single‐Atom Photocatalysts

Angewandte Chemie, EarlyView.
Increasing the density of isolated manganese (Mn) atoms in carbon nitride (CNx) photocatalysts does not continuously improve performance. Instead, beyond a critical loading, the polymer support reorganizes, altering charge‐carrier dynamics and oxygen activation while preserving atomic dispersion.
Viktoria Velichko, Agustín de Arriba, Areti Moutsiou, Elisabetta Inico, Andrea Olivati, Berta Pérez‐Román, Jesús López‐Sánchez, Ik Seon Kwon, Andrea Tonelli, Abhijit Roy, Valentina De Renzi, Raul Arenal, Annamaria Petrozza, Carlo Cavallotti, Gianvito Vilé   +14 more
wiley   +2 more sources

Omicron, the great escape artist [PDF]

Nature Reviews Immunology, 2022
Less than a month after the sequence of the SARS-CoV-2 Omicron variant was first announced, a number of articles in Nature and Cell examine its immune evasion characteristics.
openaire   +2 more sources

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Acceptability and feasibility of a comprehensive fall prevention model for independent older adults: A qualitative evaluation

International Journal of Nursing Studies Advances
Background: Falls amongst the elderly represent a global public health challenge because of their potential to cause illness, death, and reduce the autonomy of this group.
Francisca Marquez-Doren, Camila Lucchini-Raies, Claudia Alcayaga, Claudia Bustamante, Marcela González-Agüero   +4 more
doaj   +1 more source

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype [PDF]

, 2022
Variant of concern (VOC) Omicron-BA.1 has achieved global predominance in early 2022. Therefore, surveillance and comprehensive characterization of Omicron-BA.1 in advanced primary cell culture systems and animal models are urgently needed.
Berenguer Veiga, Inês, Ochsenbein, Sarah, Aguiar Moreira, Etori, Machahua, Carlos, Lang, Reto M., Barut, G Tuba, Alves, Marco P., Ebert, Nadine, Schmied, Kimberly, Dorn, Patrick, Lang, Reto M, Barut, Tuba, Oliveira Esteves, Blandina I, Leborgne, Nathan Georges François, Zumkehr, Beatrice, Devisme, Christelle, Kelly, Jenna N, Godel, Aurélie, Dijkman, Ronald, Hoffmann, Donata, Moreira, Etori Aguiar, Wylezich, Claudia, Höper, Dirk, Thiel, Volker, Kelly, Jenna N., Hoffmann, Bernd, Steiner, Silvio, Funke-Chambour, Manuela, Brügger, Melanie, Beer, Martin, Taddeo, Adriano, Esteves, Blandina I. Oliveira, Marti, Thomas M., Barut, G. Tuba, Thomann, Lisa, Halwe, Nico, Flück, Vera, Wernike, Kerstin, Trüeb, Bettina Salome, Benarafa, Charaf, Schön, Jacob, Kratzel, Annika, Alves, Marco P, Widera, Marek, Wider, Manon, Oliveira Esteves, Blandina I., Marti, Thomas M, Stalder, Hanspeter, Rauch, Andri, Ulrich, Lorenz, Beilleau, Guillaume, Halwe, Nico Joel, Veiga, Inês Berenguer, Ciesek, Sandra, Breithaupt, Angele   +54 more
core   +3 more sources

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Death and hospital contact in a cohort from Thyborøn-Harboøre an environmentally contaminated site in Denmark

Scientific Reports
We studied mortality and hospital contact in people from Thyborøn-Harboøre, an environmentally contaminated fishing community on the Danish West Coast.
Elsebeth Lynge, Hans Holmsgaard, Jørgen Bjerggaard Jensen, Søren Lophaven   +3 more
doaj   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source