Results 71 to 80 of about 254,235 (292)
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
Advanced Science, EarlyView.A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Implementation of Omnibus Policy on kindergarten education
Asian Journal of Assessment in Teaching and Learning, 2020 The implementation Omnibus Policy on Kindergarten Education was conducted primarily to determine the extent the implementation of the provisions stipulated in the DepEd Order no. 47, series 2016.
Angelito Estoesta Alvarado +1 more
doaj +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao +7 more
wiley +1 more source
Records of Australian Tramways And Motor Omnibus Employees' Association, Victorian Branch
, 1911 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Australian Tramways And Motor Omnibus Employees' Association, Victorian Branch
core +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
The Chicago public library omnibus project engaged in the production of library reference tools.
, 1940 Reproduced from type-written copy.By an error, two pages are numbered 15.Cover-title: Library service in the work of the Chicago public library WPA omnibus project.At head of title: Federal works agency.
Chicago Public Library Omnibus Project.
core
Advanced Science, EarlyView.Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong +20 more
wiley +1 more source
Who Bears the Burden? The Digital Omnibus and the Redistribution of Supervisory Costs
European Journal of Risk RegulationThe Digital Omnibus package is presented as a technical simplification of the digital rulebook, with significant estimated savings for both businesses and public administrations.
Antonio Davola, Lorenzo Rodio Nico
doaj +1 more source
Omnibus Tests for Multivariate Normality of Observations and Residuals [PDF]
This paper provides omnibus tests for multivariate normality of both observations and residuals. They are derived by considering as the alternatives to the multivariate normal a class of maximum-entropy distributions studied elsewhere by the author.
Urzúa, Carlos M.
core