Results 61 to 70 of about 5,745 (195)

Association of GLP‐1 Receptor Agonists With Hepatic Decompensation in the All of Us Research Program

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) initiation and the risk of hepatic decompensation compared with dipeptidyl peptidase 4 inhibitors (DPP4is) in a racially and ethnically diverse cohort of adults with Type 2 diabetes.
Inyoung Hwang, Yun Kim, Sang Won Lee
wiley   +1 more source

Enabling data sharing and utilization for African population health data using OHDSI tools with an OMOP-common data model

open access: yesFrontiers in Public Health, 2023
The COVID-19 pandemic has spurred the use of AI and DS innovations in data collection and aggregation. Extensive data on many aspects of the COVID-19 has been collected and used to optimize public health response to the pandemic and to manage the ...
Sylvia Kiwuwa-Muyingo   +4 more
doaj   +1 more source

Analysis of treatment pathways for three chronic diseases using OMOP CDM [PDF]

open access: yesJournal of Medical Systems, 2018
The present study examined treatment pathways (the ordered sequence of medications that a patient is prescribed) for three chronic diseases (hypertension, type 2 diabetes, and depression), compared the pathways with recommendations from guidelines, discussed differences and standardization of medications in different medical institutions, explored ...
Zhang, Xin   +14 more
openaire   +2 more sources

Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency

open access: yesVox Sanguinis, EarlyView.
Abstract Transfusion medicine generates enormous volumes of data across the vein‐to‐vein continuum, spanning donor characteristics, laboratory testing, component manufacturing, logistics and recipient outcomes. The emergence of big data infrastructures, coupled with artificial intelligence (AI), offers a transformative opportunity to harness this ...
Sheharyar Raza   +6 more
wiley   +1 more source

Heart rate phase is an indicator of chronotype‐relevant circadian shifts associated with human disease: an All of Us Research Program analysis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heart rate phase (HRP) was quantified from wearable‐derived heart rate measurements. Earlier HRP was associated with pregnancy‐associated conditions, while later HRP was associated with addiction and mood, metabolic, and sleep‐related disorders in a phenome‐wide analysis.
Zachary M. Chan   +5 more
wiley   +1 more source

Transforming Primary Care Data Into the Observational Medical Outcomes Partnership Common Data Model: Development and Usability Study

open access: yesJMIR Medical Informatics
BackgroundPatient-monitoring software generates a large amount of data that can be reused for clinical audits and scientific research. The Observational Health Data Sciences and Informatics (OHDSI) consortium developed the Observational Medical Outcomes ...
Mathilde Fruchart   +5 more
doaj   +1 more source

OMOP-on-FHIR: Integrating the Clinical Data Through FHIR Bundle to OMOP CDM

open access: yes
The harmonization of the OMOP Common Data Model (CDM) with HL7 FHIR aims to enhance interoperability in clinical research by harmonizing diverse healthcare datasets. This process, referred to as OMOP-on-FHIR, leverages FHIR Bundles for real-time clinical data exchange and transforms these resources into OMOP CDM format using an ETL process.
Jayathissa, Prabath   +3 more
openaire   +2 more sources

Assessing Overall Survival Benefits in Advanced Cancers: The Role of External Comparator Cohort Studies with Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1080-1087, April 2026.
External comparator cohort (ECC) studies with real‐world data (RWD) may provide more reliable estimates of treatment differences compared to single‐arm trials (SAT), yet they face limitations such as selection bias and data heterogeneity. This study assessed the perceived strength of evidence of ECC studies compared to SAT and randomized controlled ...
Francesco Pignatti   +19 more
wiley   +1 more source

Implementasi Gugatan Legal Standing Dan Class Action Dalam Praktik Peradilan Di Indonesia [PDF]

open access: yes, 2004
The implementation of group representative accusation especially for legal standing in the practice of judge in Indonesia is still faced with the handicaps procedural technically.
Sutiyoso, B. (Bambang)
core   +1 more source

Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records. [PDF]

open access: yes, 2013
Drug-drug interactions (DDI) account for 30% of all adverse drug reactions, which are the fourth leading cause of death in the US. Current methods for post marketing surveillance primarily use spontaneous reporting systems for learning DDI signals and ...
Bauer-Mehren, Anna   +4 more
core   +5 more sources

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