Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Multidimensional factors influencing continuance usage intention of university library self-service systems: An empirical analysis based on an extended TAM-UTAUT. [PDF]
Cao K, Wang P, Zhang C, Zhao J.
europepmc +1 more source
E. coli Extracellular Matrix: A Tunable Composite With Hierarchical Structure
The complex composite‐like mechanical behavior of E. coli biofilm matrix is the result of a synergic contribution of the rigid curli and swelling pEtN‐cellulose, and emerges from specific ratio and assembly conditions. The interactions between the two fibers govern biofilm hydration and characteristic wrinkling patterns, providing crucial insights for ...
Macarena Siri +7 more
wiley +1 more source
TrialMatchAI: an end-to-end AI-powered clinical trial recommendation system to streamline patient-to-trial matching. [PDF]
Abdallah M +14 more
europepmc +1 more source
This work develops bias‐triggered conductivity relaxation as a novel technique to study oxygen reactions in mixed ionic‐electronic conducting thin films by integrating electrochemical titration and electrical conductivity relaxation to achieve synchronous multi‐parameter characterization, providing simultaneous electronic, ionic, and extraordinarily ...
Alexander Stangl +4 more
wiley +1 more source
Mind the gap: challenges and future directions for content-based image retrieval in clinical radiology. [PDF]
Spada E +4 more
europepmc +1 more source
A reversible, all‐optical modulation strategy enables resist‐free, sub‐diffraction nanolithography of halide perovskite films. Leveraging 800 nm fs laser‐induced crystallization and 365 nm laser driven decomposition, reconfigurable patterning achieves feature sizes down to 93.5 nm. This chemistry‐free approach offers dynamic control over optoelectronic
Zhengfen Wan +4 more
wiley +1 more source
On optimisation of Paganin's method for propagation-based X-ray phase-contrast imaging and tomography. [PDF]
Gureyev TE +3 more
europepmc +1 more source
We report a wearable photonic patch integrating room light‐ and sunlight‐activatable luminescent particles (RSLPs) for both photochemical tissue bonding and photobiomodulation. RSLPs harvest ambient light and emit red luminescence to drive chlorin e6–mediated collagen crosslinking.
Kyungjoo Jo +12 more
wiley +1 more source
Deep Learning for Content-Based Medical Image Retrieval in Picture Archiving and Communication Systems for Brain Tumor Detection: Algorithm Development and Validation. [PDF]
Lee CL +5 more
europepmc +1 more source

