Results 111 to 120 of about 529,780 (298)

Neurocognitive impairment after off-pump and on-pump coronary artery bypass graft surgery – an Iranian experience

Neuropsychiatric Disease and Treatment, 2010
Mehdi Farhoudi1, Kaveh Mehrvar2, Abbas Afrasiabi3, Rezayat Parvizi3, Ahmad Ali Khalili3, Babak Nasiri3, Khosrow Hashemzadeh3, Kamyar Ghabili41Neurosciences Research Center, Imam Reza Hospital, 2Razi Hospital, 3Cardiovascular Research Center ...
Mehdi Farhoudi, Kaveh Mehrvar, Abbas Afrasiabi, et al   +3 more
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery Outcomes During 6 Years: A Prospective Cohort Study

Acta Medica Iranica, 2017
Given the ongoing controversy over the risks and benefits of on-pump versus off-pump coronary artery bypass graft surgery (CABG), we aimed to compare time trends in off- and on-pump CABG long-term outcomes.
Ahmad Amouzeshi, Zahra Amouzeshi, Mohammad Abbasi Teshnizi, Ali Asghar Moeinipour, Mahmood Hosseinzadeh Maleki   +4 more
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Summary, study of pump discharge pressure oscillations [PDF]

Analytical data on pump-generated pressure, flow, blade wake, cavitation, and stall oscillations for application to turbopump ...
Jackson, E. D.
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Impact of On-pump Versus Off-pump Coronary Artery Bypass on Oxidative Stress and Postoperative Atrial Fibrillation

Kardiyovasküler Tıp E Dergisi/E Journal of Cardiovascular Medicine
Objectives: Postoperative atrial fibrillation (POAF) is common after coronary artery bypass grafting (CABG). Gamma-glutamyl transferase (GGT), an index of oxidative injury, could provide predictive information regarding POAF.
Emced Khalil
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Comparison of outcomes between off-pump versus on-pump coronary artery bypass surgery in elderly patients: a meta-analysis

Brazilian Journal of Medical and Biological Research
The aim of this study was to analyze if off-pump coronary artery bypass surgery (CABG) is associated with better treatment outcomes in elderly patients (>70 years of age) than on-pump CABG, using meta-analysis.
Z.G. Zhu, W. Xiong, J.L. Ding, J. Chen, Y. Li, J.L. Zhou, J.J. Xu   +6 more
doaj   +1 more source