Results 61 to 70 of about 526,829 (297)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Cavity Q, mode volume, and lasing threshold in small diameter AlGaAs microdisks with embedded quantum dots [PDF]

, 2005
The quality factor (Q), mode volume (Veff), and room-temperature lasing threshold of microdisk cavities with embedded quantum dots (QDs) are investigated.
Borselli, Matthew, Krishna, Sanjay, Painter, Oskar, Srinivasan, Kartik, Stintz, Andreas   +4 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Long-term analysis of ventricular function in patients with symptomatic coronary disease who underwent on-pump or off-pump coronary artery bypass grafting

Journal of Cardiothoracic Surgery, 2022
Background Systemic deleterious effects of cardiopulmonary bypass have been observed in the postprocedural period. Long-term assessment, including ventricular function (VF), is unclear.
Rafael Rocha Mol Silva, Whady Hueb, Eduardo Gomes Lima, Paulo Cury Rezende, Paulo Rogério Soares, José Antonio Franchini Ramires, Roberto Kalil Filho   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of a plasma grating on pump-probe experiments near the ionization threshold in gases

, 2011
Calculations are performed of the phase shift caused by the spatial modulation in the plasma density due to interference between a strong pump pulse and a weak probe pulse. It is suggested that a recent experiment [Loriot et al., Opt. Express v.
Béjot, Béjot, Béjot, Chen, Couairon, Dogariu, Feng, H. M. Milchberg, J. K. Wahlstrand, Kolesik, Kolesik, Kosareva, Liu, Loriot, Loriot, Loriot, Novoa, Polynkin, Renard, Shi, Smolorz, Wahlstrand, Wang   +22 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Clinical Outcome and Cost in Patients with Off-pump vs. On-Pump Coronary Artery Bypass Surgery [PDF]

Acta Medica Iranica, 2011
General concept and major emphasis on off-pump coronary artery bypass surgery (OPCAB) is maintaining quality of care and patient safety while reducing cost and resource utilization.
Seyed Khalil Forouzannia, Mohammad Hassan Abdollahi, Seyed Jalil Mirhosseini, Habibollah Hosseini, Seyed Hossein Moshtaghion, Azam Golzar, Naeimeh Naserzadeh, Seyed Mohammad Ghoraishian, Tohid Emami Meybodi   +8 more
doaj   +1 more source

Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study. [PDF]

, 2020
Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression.
Anderson, Amanda H, Appel, Lawrence J, Chen, Jing, Feldman, Harold I, Go, Alan S, He, Jiang, Hsu, Chi-yuan, Hsu, Raymond K, Kusek, John W, Lash, James P, Liu, Kathleen D, McCulloch, Charles E, Navaneethan, Sankar D, Porter, Anna C, Rahman, Mahboob, Rao, Panduranga S, Tan, Thida C, Townsend, Raymond R, Wilson, F Perry, Xie, Dawei, Yang, Jingrong, Zhang, Xiaoming   +21 more
core  

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L, Krafft, Paul R, Leitzke, Arthur S, Tang, Jiping, Van Allen, Nicole R, Zhang, John H   +5 more
core   +1 more source