Results 201 to 210 of about 51,151,627 (314)

Carbapenem resistance in community-acquired urinary tract infections caused by <i>Klebsiella pneumoniae</i> and <i>Escherichia coli</i> in Morocco: a multicentre study (January 2022-December 2023): '<b>Carbapenem resistance in community UTIs in Morocco'</b>. [PDF]

JAC Antimicrob Resist
Khazaz A, El Otmani F, Benzaarate I, Bourjilat F, El Hamouchi A, Rafetrarivony LF, Huynh BT, Crucitti T, Brisse S, Nayme K.   +9 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance. [PDF]

Plant Genome
Jan F, Rathore M, Kumar Saini D, Singh A, Qureshi N, Aggarwal N, Bashir M, Shakeel M, Gupta V, Kumar S, Varshney RK, Mir RR.   +11 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

BT CORN AND INSECT RESISTANCE: AN ECONOMIC ASSESSMENT OF REFUGES

Genetically engineered crops offer farmers a new option for controlling pests. The high efficacy of these pesticidal crops, combined with the potential for widespread adoption, has raised concerns that pest resistance may prematurely diminish their value.
Hellmich, Richard L., Babcock, Bruce A., Hurley, Terrance M.   +2 more
core  

Integrating haplotype-enhanced HIV surveillance with national databases improves the resolution of transmission networks, drug resistance, and risk assessment. [PDF]

Emerg Microbes Infect
Cai D, Feng Y, Gan M, Li H, Wang D, Hao J, Lin L, Tang Y, Wang Y, Liao L, Wang Z, Xing H.   +11 more
europepmc   +1 more source

Resist resistance

This thesis explores changes in swallowing and communication following total laryngectomy (removal of the voice box). Chapter 1 outlines the anatomy and physiology of the pharynx and larynx, along with the functional changes that occur after the surgery.
openaire   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Optimisation and validation of capture mNGS for predicting antimicrobial resistance. [PDF]

EBioMedicine
Lin Q, Mei X, Zheng H, Meng J, He F, Yang B, Ru X, Su M, Wang D, Tan N, Fang J, Fu S, Ouyang N, Yang Z, Jiang S, Zhang Y.   +15 more
europepmc   +1 more source