Results 41 to 50 of about 28,893 (170)
The FEBS Journal, EarlyView.Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Visión Electrónica, 2021 En el mundo una de las principales causas de muertes es el cáncer pulmonar, en Estados Unidos se estimaba 135.720 muertes por cáncer pulmonar para el año 2020 sin tener en cuenta la contingencia mundial de la pandemia de Covid-19.
Leonardo González-Gutiérrez +2 more
doaj +1 more source
Italian Patients Journey for Gene Therapy in Haemophilia A
Haemophilia, EarlyView.ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno +19 more
wiley +1 more source
American Journal of Hematology, Volume 101, Issue 7, Page 1597-1604, July 2026.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Imágenes en oncología: generalidades y aplicaciones
Revista Médica Clínica Las Condes, 2013 Las imágenes tienen un rol fundamental en la oncología actual, que incluye el diagnóstico, etapificación, evaluación de respuesta al tratamiento y diagnóstico de complicaciones. El examen de mayor importancia en estos pacientes es la Tomografía Computada,
Dr. Brien S. Andrés O. +1 more
doaj +1 more source
The Prostate, Volume 86, Issue 10, Page 1170-1173, July 2026.ABSTRACT Background As overall survival improves in metastatic hormone‐sensitive prostate cancer (mHSPC), non‐cancer causes of death are increasingly relevant. Methods We conducted a real‐world multicenter study of patients diagnosed with mHSPC treated with ADT alone or in combination. Causes of death before progression to castration‐resistant prostate
Marta Garcia de Herreros +15 more
wiley +1 more source
, 2006 En el presente artículo nos vamos a centrar en el cáncer tratando de ofrecer una visión general del papel que la psicología clínica tiene en esta enfermedad.
Garrido Landívar, Emilio +1 more
core
Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?
Andrology, Volume 14, Issue 5, Page 1272-1281, July 2026.ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto +12 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source