Results 21 to 30 of about 5,158 (116)
Reseña histórica de la revista ONCOLOGÍA (Ecuador)
La revista Oncología (Ecuador) es una revista médica de acceso abierto que se publica cuatrimestralmente por la Sociedad de Lucha contra el Cáncer del Ecuador (SOLCA).
Katherine García Matamoros
doaj +1 more source
ABSTRACT Evidence to guide the treatment for patients with metastatic castration‐resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with tumor harboring HRR alterations, progressed on a prior androgen ...
Lorena Incorvaia +35 more
wiley +1 more source
INTRODUCTION: The choice of cisplatin regimen concomitant with radiotherapy (CRT) has been a matter of debate in recent years. In the adjuvant setting, the phase III JCOG 1008 trial has demonstrated non-inferiority of the weekly dose (qW) regimen in ...
Irene Bannenberg Cavero +14 more
doaj +1 more source
Biological bases of cognitive impairment induced by antinoeplastic treatment
Often patients treated with chemotherapy and/or radiotherapy suffer memory and attention problems. The exact mechanisms of action are unknown, although several explanations have been proposed. Both chemotherapy and radiotherapy have a direct toxic effect
Jaime Feliu +4 more
doaj +1 more source
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia +37 more
wiley +1 more source
El cáncer de pulmón de células no pequeñas (CPCNP) continúa siendo una de las principales causas de mortalidad por cáncer a nivel mundial. La identificación de mutaciones accionables, en especial en el gen del receptor del factor de crecimiento ...
Jessica Meza-Liviapoma +7 more
doaj +1 more source
Italian Patients Journey for Gene Therapy in Haemophilia A
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno +19 more
wiley +1 more source
Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia
ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley +1 more source
AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro +10 more
wiley +1 more source
METÁSTASIS CEREBRALES: UNA MIRADA BIOLÓGICA Y CLÍNICA
Las metástasis cerebrales son los tumores cerebrales más frecuentes y son un desafío médico. Los tumores tienen una capacidad diferente de metastatizarse en el cerebro y deben tener la capacidad de penetrar la barrera hematoencefálica, interactuar con ...
Dr. Arnaldo Marín +3 more
doaj +1 more source

