Results 21 to 30 of about 5,158 (116)

Reseña histórica de la revista ONCOLOGÍA (Ecuador)

open access: yesOncología, 2023
La revista Oncología (Ecuador) es una revista médica de acceso abierto que se publica cuatrimestralmente por la Sociedad de Lucha contra el Cáncer del Ecuador (SOLCA).
Katherine García Matamoros
doaj   +1 more source

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Evidence to guide the treatment for patients with metastatic castration‐resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with tumor harboring HRR alterations, progressed on a prior androgen ...
Lorena Incorvaia   +35 more
wiley   +1 more source

Real-life data on the use of three-weekly versus weekly cisplatin concomitant with radiotherapy in the locoregional treatment of patients with head and neck squamous cell carcinoma

open access: yesOncology in Clinical Practice
INTRODUCTION: The choice of cisplatin regimen concomitant with radiotherapy (CRT) has been a matter of debate in recent years. In the adjuvant setting, the phase III JCOG 1008 trial has demonstrated non-inferiority of the weekly dose (qW) regimen in ...
Irene Bannenberg Cavero   +14 more
doaj   +1 more source

Biological bases of cognitive impairment induced by antinoeplastic treatment

open access: yesPsicooncologia, 2012
Often patients treated with chemotherapy and/or radiotherapy suffer memory and attention problems. The exact mechanisms of action are unknown, although several explanations have been proposed. Both chemotherapy and radiotherapy have a direct toxic effect
Jaime Feliu   +4 more
doaj   +1 more source

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia   +37 more
wiley   +1 more source

¿Dónde estamos y hacia dónde vamos en el cáncer de pulmón de células no pequeñas avanzado con mutación EGFR?

open access: yesActa Médica Peruana
El cáncer de pulmón de células no pequeñas (CPCNP) continúa siendo una de las principales causas de mortalidad por cáncer a nivel mundial. La identificación de mutaciones accionables, en especial en el gen del receptor del factor de crecimiento ...
Jessica Meza-Liviapoma   +7 more
doaj   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno   +19 more
wiley   +1 more source

Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia

open access: yesThe Journal of Latin American and Caribbean Anthropology, Volume 31, Issue 4, December 2026.
ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley   +1 more source

AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro   +10 more
wiley   +1 more source

METÁSTASIS CEREBRALES: UNA MIRADA BIOLÓGICA Y CLÍNICA

open access: yesRevista Médica Clínica Las Condes, 2017
Las metástasis cerebrales son los tumores cerebrales más frecuentes y son un desafío médico. Los tumores tienen una capacidad diferente de metastatizarse en el cerebro y deben tener la capacidad de penetrar la barrera hematoencefálica, interactuar con ...
Dr. Arnaldo Marín   +3 more
doaj   +1 more source

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