Results 81 to 90 of about 48,900 (212)

Bevacizumab plus Irinotecan-Based Regimens in the Treatment of Metastatic Colorectal Cancer [PDF]

, 2010
Objectives: Bevacizumab is a monoclonal antibody that directly inhibits vascular endothelial growth factor, a key regulator of angiogenesis. Bevacizumab significantly improves progression-free and/or overall survival in metastatic colorectal cancer in ...
Heinemann, Volker, Hoff, Paulo M.
core   +1 more source

Pediatric Craniofacial Osteosarcoma: The Milano Experience

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Craniofacial osteosarcoma (CFOS) is a rare tumor, typically affecting patients over 60, with a low incidence of metastasis at diagnosis as well as at relapse. Patients and methods This study analyzed patients treated for high‐grade CFOS at Fondazione IRCCS Istituto Nazionale dei Tumori between 1991 and 2021, focusing on histological
Cristina Meazza, Francesca Parisi, Francesco Barretta, Giovanna Sironi, Olga Nigro, Carlo Morosi, Roberto Luksch, Marta Podda, Andrea Ferrari, Monica Terenziani, Filippo Spreafico, Michela Casanova, Veronica Biassoni, Elisabetta Schiavello, Antonina Parafioriti, Paola Collini, Stefano Chiaravalli, Nadia Puma, Luca Bergamaschi, Giovanna Gattuso, Valeria Colombo, Sabina Vennarini, Emilia Pecori, Marco Guzzo, Sarah Colombo, Arianna Trovò, Maura Massimino   +26 more
wiley   +1 more source

Epithelial elements in superficial angiomyxomas: mimicry of adnexal development, and mesenchymal‐to‐epithelial transition

Histopathology, Volume 87, Issue 2, Page 321-328, August 2025.
Aims A subset of superficial angiomyxomas contains epithelial elements. Rarely, especially in Carney's complex patients, arborizing adnexal proliferations are present, with some authors proposing that they could be authentic adnexal neoplasms. Our aim was to determine if the epithelial elements are trapped adnexal epithelium, epithelial outgrowths ...
Carlos Monteagudo, Liria Terrádez, Esther Alvarez, Paloma Masiá, Mónica Espino, María Ortega   +5 more
wiley   +1 more source

Perception of nursing professionals in assisting children with cancer

Revista de Enfermagem da Universidade Federal de Santa Maria, 2015
Aim: to analyze the experience of a nursing staff in the care of children with cancer in a Pediatric Unit of a University Hospital in southern Brazil. Method: it is a qualitative, descriptive and exploratory research.
Débora Maria Bastos Pereira, Karine Bertoldi, Adriana Roese   +2 more
doaj   +1 more source

O Hospital Aristides Maltez e o controle do câncer do colo do útero no Brasil [PDF]

, 2014
O Hospital Aristides Maltez (HAM) foi inaugurado em 1952 na cidade de Salvador (Bahia). O hospital era uma instituição filantrópica pertencente à Liga Baiana Contra o Câncer. Centro especializado no tratamento de variados tipos de câncer, o HAM tinha sua
Lana, Vanessa
core   +4 more sources

Total Metabolic Tumor Volume Is a Strong Independent Prognostic Factor in Follicular Lymphomas: Results From a Sub‐Study of the FOLL12 Trial

American Journal of Hematology, Volume 100, Issue 7, Page 1196-1204, July 2025.
ABSTRACT Discordant results have been generated regarding the prognostic role of Total Metabolic Tumor Volume (TMTV) in Follicular Lymphoma (FL). The use of prospective data and the adoption of the newly defined standardized SUV4 method for calculating TMTV may generate stronger evidence.
Rexhep Durmo, Stephane Chauvie, Carla Minoia, Fabrizio Bergesio, Federico Fallanca, Simona Peano, Luigi Marcheselli, Antonella Anastasia, Carola Boccomini, Paolo Corradini, Jacopo Olivieri, Luca Arcaini, Federica Cavallo, Adalberto Ibatici, Luca Nassi, Vittoria Tarantino, Antonello Pinto, Caterina Stelitano, Alessandro Pulsoni, Francesca Ricci, Salvatrice Mancuso, Emanuele Cencini, Nicola Di Renzo, Clara Mannarella, Angelo Palmas, Pierluigi Zinzani, Caterina Bocci, Francesca Rossi, Angelo Michele Carella, Massimo Federico, Annibale Versari, Luca Guerra, Stefano Luminari   +32 more
wiley   +1 more source

Hematopoietic stem cell transplantation in childhood: current status and perspectives [PDF]

, 2009
Hematopoietic stem cell transplantation is a treatment option for a large number of children with malignant and non-malignant diseases. The objective of this article is to present the current status of hematopoietic stem cell transplantation in the ...
Seber, Adriana
core   +1 more source

First‐in‐human phase 1 study of KHK2455 monotherapy and in combination with mogamulizumab in patients with advanced solid tumors

Cancer, Volume 131, Issue 13, 1 July 2025.
Abstract Background Indoleamine 2,3‐dioxygenase 1 (IDO1) is a heme‐containing enzyme that degrades tryptophan (Trp) to kynurenine (Kyn), which suppresses effector T cells and reduces antitumor activity. KHK2455 is a long‐acting selective IDO1 inhibitor that blocks the heme component of the IDO holoenzyme.
Timothy A. Yap, Olivier Rixe, Capucine Baldini, Ursa Brown‐Glaberman, Sergey Efuni, David S. Hong, Christophe Massard, Jameel Muzaffar, Andreea Varga, Emrullah Yilmaz, Yuta Ikawa, Lisa H. Shiue, Yi Liu, Matthew W. Hruska, Henry Zhao, Akihiro Tokunaga, Solmaz Sahebjam   +16 more
wiley   +1 more source

In-room test results at CNAO of an innovative PT treatments online monitor (Dose Profiler) [PDF]

, 2018
The use of C, He and O ions as projectiles in Particle Therapy (PT) treatments is getting more and more widespread as a consequence of their enhanced relative biological effectiveness and oxygen enhancement ratio, when compared to the protons one.
Battistoni G., De Simoni M., Dong Y., Embriaco A., Fischetti M., Mancini Terracciano C., Marafini M., Mattei I., Mirabelli R., Muraro S., Patera V., Sarti A., Schiavi A., Sciubba A., Solfaroli Camillocci E., Traini G., Valle S. M.   +16 more
core   +1 more source

Advanced Stage Head and Neck Cancer Diagnosis: HEADSpAcE Consortium Health Systems Benchmarking Survey

Head &Neck, Volume 47, Issue 7, Page 1977-1988, July 2025.
ABSTRACT Background Globally, most people with head and neck cancers (HNCs) are diagnosed with advanced‐stage disease. HNC diagnostic stage has multifactorial explanations, with the role of health system factors not yet fully investigated. Methods HNC centres (n = 18) from the HEADSpAcE Consortium were surveyed via a bespoke health system questionnaire
Grant Creaney, Mariél de Aquino Goulart, Alex McMahon, Claire Paterson, James McCaul, Sandra Perdomo, Laura Mendoza, Laia Alemany, Lidia Maria Rebolho Arantes, Paula Andrea Rodriguez Urrego, Tom Dudding, Mirana Pring, Marta Vilensky, Cecilia Cuffini, Silvia Adriana Lopez de Blanc, José Carlos de Oliveira, Shahid Pervez, Pierre Saintigny, Mauricio Cuello, Jaroslav Betka, Luis Felipe Ribeiro Pinto, Maria Paula Curado, Kazem Zendehdel, Lorenzo Richiardi, Maja Popovic, José Roberto de Podesta, Sandra Ventorin von Zeidler, Ricardo Mai Rocha, HEADSpAcE Consortium, Shaymaa Alwaheidi, Paul Brennan, Shama Virani, Al Ross, David I Conway, R Adam, A Agudo, W Ahrens, L Alemany, S Alibhai, M Angel‐Pavon, N Anwar, L Arantes, P. E. Arantes, L Arguello, Y Avello, L Avondet, A. M. Baldión‐Elorza, C Batista‐Daniel, B Beraldi, B Berenstein, P Bernal, N Bernardino‐Rodrigues, J Betka, K Bilic‐Zimmermann, L Bouvard, M Botta, J Brenes, N Brenner, C Brentisci, C Burtica, M Cabañas, C Canova, E Cantor, G Carretero, A Carvalho, R Carvalho, L Chiusa, P Chopard, M Choulli, Q Chundriger, O Clavero, S Coelho‐Soares‐Lima, I Costa, M Cuello, C Cuffini, M. P. Curado, A. C. de Carvalho, J. C. de Oliveira, T Dias, T Dudding, E Duccini de Souza, I. C. Durant, E Ebrahimi, A Escallón, G. A. Fernandes, B Fervers, V Fiano, F Firme‐Figueira, R Furbino‐Villefort, V Gaborieau, R Gama, M Gangemi, P Garzino‐Demo, R Giglio, A Guasch, J Graça Sant’Anna, M Grega, A Gregório‐Có, M Hadji, J. A. Hakim, N Hayes, C. M. Healy, M Homero de Sá Santos, I Holcatova, K Hurley, M Insfran, G. C. Iorio, M Iqbaluddin Siddiqui, J Johannsen, M Kaňa, J. P. Klussmann, L. P. Kowalski, A Lagiou, P Lagiou, E Legal, J Lenzi, F Luiz Dias, Lyra González, W Machado‐Zorzaneli, G. J. Macfarlane, R Mai‐Rocha, M Maños, P Marinho‐de‐Abreu, J Mckay, C Mena, L Mendoza, E. F. Mendonça, L Meza, B Michels, M. S. Mineiro, C Moccia, P Mongelos, A. L. Montealegre‐Páez, F Morey‐Cortes, A Muñoz, A Ness, A Neves, M Oliva, H Ortiz, J Ortiz, M Osorio, V Ospina, O Ostellino, M Palau, S Paytubi‐Casabona, G Pecorari, S Perdomo, D. M. Pereira, O Pérol, S Pervez, A Pomata, J Polesel, M Popovic, A Poveda, C Prado, K Prager, M Pring, G Ramieri, H Rashidian, S Rasul, J Rego, R. M. Reis, H Renard, L. F. Ribeiro‐Pinto, U Ricardi, L Richiardi, G Riva, P Rodriguez‐Urrego, M Robinson, F Rodilla, I Rodriguez, M Rodríguez, P. E. Roux, T Saeed‐Ali, P Saintigny, J. J. Santivañez, C Scapultampo‐Neto, J Segovia, A Sena, M Sepideh, R Serrano, S. J. Sharma, O Siefer, S Smart, B. P. Sorroche, C Sosa, J. D. Souza, A Stura, S Thomas, S Thoms, O Torres, S Tous, G Ucross, A Valenzuela, J. R. Vasconcelos‐de‐Podestá, M Vilensky, S Von‐Zeidler, T Waterboer, A Whitmarsh, S Wright, K Zendehdel, A Znaor   +201 more
wiley   +1 more source