Results 121 to 130 of about 1,640,336 (314)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A comprehensive welfare scoring system for graft versus host disease clinical assessment in humanised mouse models used for pharmaceutical research

Frontiers in Immunology
Immuno-oncology drug discovery increasingly relies on humanised mouse models of cancer due to limitations of murine surrogate tools and differences between mouse and human immune systems.
Alice Nowak, Rebecca Marlow, Kelli Ryan, Jean-Martin Lapointe, Daniel Sutton, Alan Sharpe, Lucy Crook, Jennifer A. Walker, Emma Little, John Peverill, Adam Holberry-Brown, Emma Wassell, Robbie McLaren-Jones, Chelsea Cavanagh, Alex Vlad Dobre, Tamara Baker, Matthew Clayton, Natasha A. Karp, Michiel Plugge, Aurélie A. Thomas, Simon J. Dovedi, Suzanne I. Sitnikova, Natalie Burrows   +22 more
doaj   +1 more source

PAIN MANAGEMENT IN LUNG CANCERS : EXPERIENCE OF THE MEDICAL ONCOLOGY DEPARTMENT OF HASSAN II HOSPIATL IN FEZ

, 2023
I. Stitou, Oumaima Siyouri, Karima Alaoui Ismaili, M. Ismaili, L. Amaadour, K. Oualla, S. Arifi, Z. Benbrahim, N. Mellas   +8 more
openalex   +1 more source

Tumour-associated macrophages as treatment targets in oncology

Nature Reviews Clinical Oncology, 2017
A. Mantovani, F. Marchesi, A. Malesci, L. Laghi, P. Allavena   +4 more
semanticscholar   +1 more source

Radiotheranostics in oncology: current challenges and emerging opportunities

Nature Reviews Clinical Oncology, 2022
L. Bodei, K. Herrmann, H. Schöder, A. Scott, Jason S. Lewis   +4 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

IROCA-TES: Improving Quality in Radiation Oncology through Clinical Audits — Training and Education for Standardization

, 2023
Julian Malicki, Carla Lopez Castro, Magdalena Fundowicz, Marco Krengli, C. Llacer-Moscardo, Sebastian Curcean, Carles Muñoz‐Montplet, Luísa Carvalho, Ewelina Konstanty, Tania Patricia Hernández Barragán, Carla Pisani, Peter Laszlo, Miquel Macià Garau, Marta Kruszyna‐Mochalska, Joana Lencart, Dorota Zwierzchowska, A Soler Roselló, Adelina Brezae, Eva Varela, Piotr Milecki, Micol Zannetti, Coza Ovidiu, Eva González, Debora Beldì, Ferrán Guedea   +24 more
openalex   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Oncology meets immunology: the cancer-immunity cycle.

Immunity, 2013
Daniel S. Chen, I. Mellman
semanticscholar   +1 more source