Results 121 to 130 of about 1,580,994 (358)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Pathology and Oncology Research, 2023 Pathology and Oncology Research Editorial Office
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The chick embryo chorioallantoic membrane assay as a model for the study of angiogenesis
Bioscience Journal, 2019 Angiogenesis is a fundamental physiological process with strong implications in tissue homeostasis. Animal models helping to identify how angiogenesis is regulated are fundamental to answer many biological questions.
Angélida Daiane Lemos do Prado +6 more
doaj
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Preoperative radiation therapy(a plan for combined therapy by the radiation therapy oncology group and the central oncology group) [PDF]
, 1974 Luther W. Brady +5 more
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Annals of Surgery Open, 2022 Esha Pai, MBBS, MS (General Surgery), MCh. (Surgical Oncology), MRCS +1 more
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Modern Radiotherapy and Oncology. Malignant Diseases in Children [PDF]
, 1975 openalex +1 more source