Results 181 to 190 of about 1,640,336 (314)

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Nature Cancer, 2020
S. M. Corsello, Rohith T. Nagari, R. Spangler, J. Rossen, M. Kocak, Jordan G. Bryan, Ranad Humeidi, David Peck, Xiaoyun Wu, A. Tang, Vickie M. Wang, Samantha A Bender, E. Lemire, Rajiv Narayan, Philip Montgomery, U. Ben-David, C. Garvie, Yejia Chen, M. Rees, Nicholas J. Lyons, James M. McFarland, Bang Wong, Li R. Wang, N. Dumont, Patrick J O'Hearn, Eric Stefan, John G Doench, C. Harrington, H. Greulich, M. Meyerson, F. Vazquez, A. Subramanian, J. Roth, Joshua A. Bittker, J. Boehm, C. Mader, Aviad Tsherniak, T. Golub   +37 more
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

The development of enzyme- and light-responsive compounds to enable novel theranostic approaches in oncology [PDF]

Ilse M. Welleman
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Correction: Mammographic density and breast cancer pathological subtypes by menopausal status and body mass index. [PDF]

Breast Cancer Res
Fernández-Morata J, Pollán M, Fernández de Larrea-Baz N, Pachón-Olmos V, García-Pérez J, Castelló A, Sierra MÁ, Lucas P, Llobet R, Stradella A, Cantos B, Ramón Y Cajal T, Santisteban M, Seguí MÁ, Santaballa Bertrán A, Granja M, Camps-Herrero J, Recalde S, Nuñez-García B, Calvo Verges N, Pérez-Gómez B, Pastor-Barriuso R, Lope V.   +22 more
europepmc   +1 more source

Decreasing Patient Wait Time by Process Level Interventions in an Oncology Daycare Unit: A Quasi‐Experimental Study

Avani Radheshyam, Vinod K. Ramani, Manohar Mhaske, Radheshyam Naik   +3 more
openalex   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

A call to action: improving access to cardiac MRI for diagnosis of immune checkpoint inhibitor related myocarditis in low and middle income countries. [PDF]

Cardiooncology
Ghose A, Kandala A, Sabnis I, Hasanova M, Simela C, Manisty C, Banerjee S, Szmit S, Westwood M, Macedo AVS, Martinez DS, Daniele AJ, Noronha V, Singh T, Ky B, Adeleke S, Maniam A, Casselli SJ, Lenihan DJ, Dent S, Ghosh AK.   +20 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Retraction: Effects of gallotannin-enriched extract of Galla Rhois on the activation of apoptosis, cell cycle arrest, and inhibition of migration ability in LLC1 cells and LLC1 tumors

Pathology and Oncology Research
Pathology and Oncology Research Editorial Office
doaj   +1 more source