Results 211 to 220 of about 1,580,994 (358)

Retraction: The Plasmodium circumsporozoite protein, a novel NF-κB inhibitor, suppresses the growth of SW480

Pathology and Oncology Research
Pathology and Oncology Research Editorial Office
doaj   +1 more source

Development and Pilot Testing of PrOFILE-ST: A Pediatric Surgical Oncology Capacity and Quality Assessment Tool for Resource-Limited Settings. [PDF]

Cancer Med
de Souza FKM, de Campos Vieira Abib S, Ribeiro RC, de Campos DR, Gallo LS, De la Cruz RR, Shalkow-Klincovstein J, Ponce-Cruz J, Elnour M, Ngongola A, Kalota S, Bvulani B, Houston L, Misal R, Forrest H, Sullivan N, Alvarez A, Naradasu S, Maru A, Gonzalez-Guzman ML, Friedrich P, Abdelhafeez A.   +21 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Precision oncology for advanced-stage adenocarcinoma of the appendix: comprehensive molecular characterisation identifies actionable lesions and potential predictive biomarkers. [PDF]

BMJ Open Gastroenterol
Lange S, Lisiecki H, Kreutzfeldt S, Heining C, Weiss L, Westphalen CB, Stenzinger A, Hübschmann D, Jesinghaus M, Glimm H, Fröhling S, Pfarr N, Schlitter AM.   +12 more
europepmc   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Combination chemotherapy of advanced colorectal cancer utilizing 5-fluorouracil, semustine, dacarbazine, vincristine, and hydroxyurea: A phase III trial by the eastern cooperative oncology group (EST: 4275) [PDF]

, 1982
Paul F. Engstrom, John Macintyre, Harold O. Douglass, Franco M. Muggia, Arnold Mittelman   +4 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Ideas for mentorship in oncology for medical students and early career doctors: insights from a UK-wide oncology mentorship scheme. [PDF]

BMC Med Educ
Kucharczak J, Khoury EG, Toiber Kent Y, Winayak R, Duke S.   +4 more
europepmc   +1 more source

Overtreatment of children with Wilms' tumour outside paediatric oncology centres. [PDF]

, 1989
Jon Pritchard, Charles Stiller, E L Lennox   +2 more
openalex   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source