Results 221 to 230 of about 2,436,024 (405)

An analysis of palliative care in adolescents and young adults with soft tissue and bone sarcomas. [PDF]

open access: yesPalliat Care Soc Pract
Wytiaz V   +5 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Correction: Laparoscopic Versus Robotic Adrenalectomy: A Randomized Clinical Trial. [PDF]

open access: yesAnn Surg Oncol
Berber E   +4 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Metachronous Pheochromocytoma and Cholangiocarcinoma in a patient with Neurofibromatosis type 1: a case report. [PDF]

open access: yesOxf Med Case Reports
Al Harrak Y   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Correction: Circulating tumor DNA refines consolidation immunotherapy for limited-stage small cell lung cancer patients. [PDF]

open access: yesSignal Transduct Target Ther
Yang Y   +20 more
europepmc   +1 more source

Positron-emission tomography/computed tomography imaging in head and neck oncology: An update

open access: diamond, 2016
Viet D. Nguyen   +3 more
openalex   +1 more source

Home - About - Disclaimer - Privacy