Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Application of artificial intelligence in gynecologic cancers: A bibliometric analysis. [PDF]
Liu N, Jiang F, Lou Y, Guan J.
europepmc +1 more source
432 A drop of insight: single cell functional profiling for immuno-oncology [PDF]
Adam Glaser +13 more
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Advances in End-of-Life Care in Canada: Implications for Oncology Nursing. [PDF]
Booker R, Lelond S, Stilos K.
europepmc +1 more source
Polymeric nanoparticles for targeted treatment in oncology: current insights
Prabhu RH, Patravale VB, Joshi MD
openalex +1 more source
Education paths in neuro-oncology: combining technical skills with multidisciplinary care. A survey from the AINO (Italian Association for Neuro-Oncology) Youngster Committee [PDF]
Rina Di Bonaventura +15 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Development and pilot evaluation of a Psychosocial Oncology and Palliative Care Training program for nurses in Cameroon. [PDF]
Bassah N +12 more
europepmc +1 more source

