Results 161 to 170 of about 5,125,322 (307)

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Patient Experience on a Hospital Oncology Service Before and After Implementation of a No-Visitor Policy During COVID-19. [PDF]

J Patient Exp, 2021
Bolton KC, Lawler M, Hauptman J, Madden M, DeVoe SG, Kennedy AG, Tomkins BJ, Hodde NM.   +7 more
europepmc   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

The Operation of Canada's Only Virtually Operated Radiation Oncology Service During the COVID-19 Pandemic. [PDF]

Adv Radiat Oncol, 2021
Romani C, Conlon M, Oliver M, Leszczynski K, Hunter M, Lam K, Spadafora S, Pearce A.   +7 more
europepmc   +1 more source

Report of the Public Service Commission of New Hampshire.

, 1911
Report year irregular.Mode of access: Internet.Split into: Statistical report of the Public Service Commission of New Hampshire, and: Reports and orders of the Public Service Commission of the State of New Hampshire for the period ending ..
New Hampshire. Public Service Commission.
core  

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

Advanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao, Zheyi Ji, Chang He, Jiying Wang, Xiaoming Luo, Junyi Liu, Xiaohu Jing, Fang Yan, Yirong Chen, Linhao Qu, Sen Yang, Le Lu, Yuming Jiang, Xiyue Wang, Chengyun Dou, Junhan Zhao   +15 more
wiley   +1 more source

Comparison of Nationwide Volumes for Five Major Gastrointestinal Surgical Procedures in Japan: Implications From Publicly Available NCD and NDB Open Data

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim In Japan, the National Clinical Database (NCD), a clinician‐reported registry, and the National Database of Health Insurance Claims and Specific Health Checkups of Japan Open Data (NDB Open Data), an administrative claims database, are both widely used as nationwide surgical databases, but their consistency in capturing national surgical ...
Atomu Kiriyama, Masakazu Fujii, Toshimichi Asano, Satoshi Hirano   +3 more
wiley   +1 more source

Integration of a patient-centred MUO/CUP service within a new acute oncology service: challenges and rewards. [PDF]

Future Healthc J, 2021
Dasgupta S, Hyland WB, Haughey C, Mughal S, Henry A, Diver-Hall C.   +5 more
europepmc   +1 more source

Minnesota Feed Service, 1967 Winter

, 1967
University of Minnesota, Agricultural Extension Service; Otto, Harley J.. (1967). Minnesota Feed Service, 1967 Winter.
Otto, Harley J., University of Minnesota, Agricultural Extension Service   +1 more
core  

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source