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Low dose ondansetron with dexamethasone for prophylaxis of postoperative nausea and vomiting following laparoscopic cholecystectomy-A randomized double-blind study. [PDF]

J Anaesthesiol Clin Pharmacol
Chilkoti GT, Nandanan J, Saxena AK, Seth V, Kaur N, Maurya P.   +5 more
europepmc   +1 more source

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Ondansetron

European Journal of Cancer, 1993
Ondansetron is the first selective antagonist of the 5-hydroxytryptamine receptors (type 3) marketed for the prevention of emesis induced by antineoplastic agents. Ondansetron has been shown to be more active and less toxic than high-dose metoclopramide in patients submitted to cisplatin chemotherapy.
F, Roila, M, Tonato, C, Basurto, S, Bracarda, M, Sassi, M, Lupattelli, M, Picciafuoco, E, Ballatori, A, Del Favero   +8 more
openaire   +4 more sources

Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis.

Birth Defects Research, 2020
Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy. The main objective of this study was to evaluate the risk of major congenital malformations (MCM), cardiac defects and orofacial clefts associated with first ...
C. Picot, A. Bérard, G. Grenet, E. Ripoche, M. Cucherat, J. Cottin   +5 more
semanticscholar   +1 more source

Comparisons of aprepitant and ondansetron

American Journal of Health-System Pharmacy, 2007
We are responding to the letter from Cavaretta and Noviasky[1][1] concerning Merck’s two Phase III studies of aprepitant 40 mg p.o. versus ondansetron 4 mg (as the hydrochloride salt) i.v. in the prevention of postoperative nausea and vomiting (PONV).[2][2],[3][3] Prophylactic ondansetron ...
Theodore F. Reiss, Christopher Lines, Alexandra D. Carides, Pierre Diemunsch, Bernadette McKeon   +4 more
openaire   +3 more sources

Ondansetron [PDF]

Drugs, 1991
Ondansetron (GR 38032F) is a highly selective 5-HT3 receptor antagonist, one of a new class of compounds which may have several therapeutic applications. Animal and clinical studies show that ondansetron reduces the 24-hour incidence and severity of nausea and vomiting induced by cytotoxic drugs, including cisplatin, and by single exposure, high dose ...
Rennie C. Heel, Richard J. Milne
openaire   +2 more sources