Results 51 to 60 of about 29,325 (273)

Comparison of the antiemetic effect of ramosetron with the combination of dexamethasone and ondansetron in middle ear surgery: A double-blind, randomized clinical study

Saudi Journal of Anaesthesia, 2013
Background: Postoperative nausea and vomiting (PONV) is a frequent complication of middle ear surgery. Ondansetron has been shown to be effective for early PONV and dexamethasone has been shown to be effective for late PONV.
Sameer Desai, M. C. B. Santosh, Rashmi Annigeri, V B Santoshi, Raghavendra Rao   +4 more
doaj   +1 more source

Ondansetron in dogs with nausea associated with vestibular disease: A double‐blinded, randomized placebo‐controlled crossover study

Journal of Veterinary Internal Medicine, 2022
Background Nausea and emesis can be, among other signs, common manifestations of acute vestibular system dysfunction in dogs. Currently, antiemetic drugs, such as maropitant and metoclopramide, are used commonly, but do not appear to control nausea.
Lea Henze, Sarah Foth, Sebastian Meller, Friederike Twele, Marios Charalambous, Hannah Kenward, Jonathan Elliott, Ludovic Pelligand, Holger A. Volk   +8 more
doaj   +1 more source

Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries: A triple blind randomized controlled trial

Medicina Oral, 2018
Background The aim of this randomized controlled triple blind trial was to compare the efficacy of clonidine with dexamethasone versus ondansetron with dexamethasone for postoperative pain, nausea and vomiting prevention in orthognathic surgery patients.
Sahand Samieirad, Alireza Sharifian-Attar, M. Eshghpour, Vajiheh Mianbandi, Elaheh Shadkam, Majid Hosseini-Abrishami, Mayam-Sadat Hashemipour   +6 more
semanticscholar   +1 more source

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,4‐dioic acid (SSDA) and 4‐OH‐solanidine as diet‐derived cytochrome P450 2D6 (CYP2D6) biomarkers in a ...
Jens Andreas Sarömba, Julian Peter Müller, Jolanta Tupiec, Anjali Roeth, Berkan Kurt, Florian Kahles, Thea Laurentius, Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

GDF15 Analogues Acting as GFRAL Ligands

ChemMedChem, EarlyView.
Considering the great importance of the GDF15/GRAL/RET signalling pathway, this review focuses on GDF15‐derived analogues able to act either as GFRAL agonists or antagonists, investigating their possible pharmacological applications in the treatment of GDF15‐related conditions, such as obesity and diabetes (agonist), or cancer‐induced nausea and ...
Andrea Di Santo, Livio Tarchi, Gianluca Villa, Giovanni Castellini, Valdo Ricca, Roberta Squecco, Anna Maria Papini, Feliciana Real‐Fernandez, Paolo Rovero   +8 more
wiley   +1 more source

Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study

BMC Veterinary Research, 2017
BackgroundNausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and ...
H. Kenward, J. Elliott, Terry Lee, L. Pelligand   +3 more
semanticscholar   +1 more source

QTc Interval Changes in Preeclampsia vs. Normal Pregnancy: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy induces significant adaptations in the cardio‐autonomic nervous system, with additional cardiac stress in preeclampsia potentially impacting ventricular repolarization. Despite the widespread use of QT‐prolonging drugs during pregnancy, the extent of heart rate (HR)‐corrected QT (QTc) interval changes during normal pregnancy and preeclampsia ...
Omar A. Aboshady, Jess Z. Raffa, Sara K. Quinney, James E. Tisdale, Brian R. Overholser   +4 more
wiley   +1 more source

A comparison between intravenous ondansetron and granisetron in the preventive management of postoperative nausea and vomiting in patients undergoing cesarean section under spinal anesthesia

Bali Journal of Anesthesiology, 2021
Background: Efforts are still conducted to reduce side effects of anesthesia, such as postoperative nausea and vomiting (PONV). This study was performed to compare the effectiveness of prophylactic use of intravenous Ondansetron (4 mg) and Granisetron (2
Lakshmi Deepthi Parripati, Seshatalpa Sai Bandarupalli, Manoj Ramella, L Sandhya   +3 more
doaj   +1 more source

Comparing Ondansetron with Ondansetron-Dexamethasone Combination on Postoperative Nausea and Vomiting after Elective Abdominal Surgeries: A Randomized Double Blinded Clinical Trial

Archives of Anesthesia and Critical Care, 2018
Background: Postoperative nausea and vomiting (PONV) is an unpleasant and distressing complication after abdominal surgeries. We conducted a study to compare the efficacy of Ondansetron-Dexamethasone combination with ondansetron alone on PONV after ...
Sussan Soltani Mohammadi, Zahra Gholamhosseinzadeh Tabasi   +1 more
doaj  

Comparison of Efficacy of Clonidine versus Ondansetron for Prevention of Nausea and Vomiting Post Thyroidectomy: A Double Blind Randomized Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background and Aim: Postoperative nausea vomiting (PONV) is the most common symptom in patients post thyroidectomy. Literature search shows conflicting results regarding use of clonidine in PONV prophylaxis.
Setty Nagendra Gupta Shilpa, Sampangiramaiah Shailaja, Selvaraj Shanthini Hilda   +2 more
doaj   +1 more source