Results 51 to 60 of about 36,355 (226)

Methotrexate toxicity and intolerance in paediatric inflammatory bowel disease: A retrospective cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Methotrexate (MTX) is frequently prescribed in paediatric inflammatory bowel disease (IBD), with routine laboratory monitoring to detect adverse events (AEs), such as hepatotoxicity and myelotoxicity. However, data on the incidence and predictors of these AEs remain limited.
Eva Vermeer, Eveline L. Soetens, Eduard A. Struys, Johan E. van Limbergen, Maja Bulatović‐Ćalasan, Robert de Jonge, Nanne K. H. de Boer, Tim G. J. de Meij   +7 more
wiley   +1 more source

A Physiologically Based Pharmacokinetic Model to Predict Systemic Ondansetron Concentration in Liver Cirrhosis Patients

Pharmaceuticals, 2023
Introduction: Ondansetron is a drug that is routinely prescribed for the management of nausea and vomiting associated with cancer, radiation therapy, and surgical operations. It is mainly metabolized in the liver, and it might accumulate in patients with
Faleh Alqahtani, Abdullah H. Alruwaili, Mohammed S. Alasmari, Sultan A. Almazroa, Khaled S. Alsuhaibani, Muhammad F. Rasool, Abdulkarim F. Alruwaili, Sary Alsanea   +7 more
doaj   +1 more source

Acupressure on Zusanli (St36) and Taibai (Sp3) in Reducing Nausea for Patients with Dyspepsia at Banyumas Hospital [PDF]

, 2014
Background: Nausea is unpleasant sensation behind the throat and epigastrium often causing vomiting. Nausea is a major symptom in patients with dyspepsia. Typical treatments for nausea are antiemetic drugs and non-pharmacological therapy.
Achiriyati, D. (Deny), Mardiyono, M. (Mardiyono), Oktaviani, R. (Rizky)   +2 more
core  

Interventions for treating hyperemesis gravidarum. [PDF]

, 2016
BACKGROUND: Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0.3% to 1.0% of pregnancies, and is one of the most common indications for hospitalization during pregnancy.
Abas, Adamczak, Arsenault, Bailit, Bondok, Bowen, Capp, Carlsson, Cox, Ditto, Dodds, Duggar, Eftekhari, Eliakim, Erez, Fell, Ferruti, Fischer-Rasmussen, Fletcher, Fletcher, Gadsby, Gawande, Gill, Goodwin, Gordon, Habek, He, Heazell, Holmgren, Ismail, Jarvis, Kashifard, Kelly, Klebanoff, Koren, Koren, Koren, Koren, Kramer, Lask, Ling, Liu, Magee, Maina, Maltepe, Maltepe, Mao, Mao, Matok, Matok, Matthews, Mazzotta, McCarthy, McCarthy, McParlin, Mella, Miller, Moran, Munch, Nelson-Piercy, Neri, Neutel, Niebyl, Oliveira, Ozgoli, Pasternak, Philip, Piwko, Pongrojpaw, Poursharif, Poursharif, Power, Price, Rhodes, Rhodes, Rosen, Safari, Safari, Saha, Shin, Shin, Sonkusare, Sullivan, Sullivan, Swallow, Tabatabaii, Tan, Tan, Tan, Tasci, Veciana, Wibowo, Willetts, Ylikorkala, Yost, Zhou, Ziaei   +96 more
core   +2 more sources

Maralixibat for the treatment of severe xanthomas in two children with Alagille syndrome: Case reports

JPGN Reports, EarlyView.
Abstract Alagille syndrome (ALGS) is a rare, autosomal dominant disorder which presents with a broad range of clinical manifestations, including cholestatic pruritus. A unique manifestation of ALGS is the presence of xanthomas in 24%–42% of patients, which can lead to liver transplantation.
Geetanjali Bora, Ruben E. Quiros‐Tejeira, Bernadette Vitola   +2 more
wiley   +1 more source

Comparison of aprepitant versus ondansetron for prevention of postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis

Indian Journal of Anaesthesia
Background and Aims: Postoperative nausea and vomiting (PONV) is a common complication after surgery. Preventing PONV in high-risk patients often requires a multimodal approach combining antiemetic drugs with diverse mechanisms.
Madhusudan P. Singh, Meenalotchini P. Gurunthalingam, Ayushee Gupta, Juhi Singh   +3 more
doaj   +1 more source

Comparison of Efficacy of Clonidine versus Ondansetron for Prevention of Nausea and Vomiting Post Thyroidectomy: A Double Blind Randomized Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background and Aim: Postoperative nausea vomiting (PONV) is the most common symptom in patients post thyroidectomy. Literature search shows conflicting results regarding use of clonidine in PONV prophylaxis.
Setty Nagendra Gupta Shilpa, Sampangiramaiah Shailaja, Selvaraj Shanthini Hilda   +2 more
doaj   +1 more source

Overnight Monitoring After T&A for Children Ages 24–36 Months: Is It Always Necessary?

The Laryngoscope, EarlyView.
This study aims to identify whether all children < 3 years of age require overnight admission after tonsillectomy with or without adenoidectomy. We found that 98.7% of children who were off oxygen within 3 h after surgery never went back on oxygen during the entire monitoring period.
Tyler Van Heest, Luka Bahra, Suhong Tong, Regina Hofner‐Hnotz, Norman Friedman   +4 more
wiley   +1 more source

Applicability of the National Comprehensive Cancer Network/Multinational Association of Supportive Care in Cancer Guidelines for Prevention and Management of Chemotherapy-Induced Nausea and Vomiting in Southeast Asia: A Consensus Statement. [PDF]

, 2017
A meeting of regional experts was convened in Manila, Philippines, to develop a resource-stratified chemotherapy-induced nausea and vomiting (CINV) management guideline. In patients treated with highly emetogenic chemotherapy in general clinical settings,
Abdullah, Matin M, Chan, Alexandre, Ishak, Wan Zamaniah B Wan, Kanesvaran, Ravindran, Ong-Cornel, Annielyn B, Villalon, Antonio H   +5 more
core   +2 more sources

A Systematic Review of the Parkinson's Foundation Hospital Care Recommendations

Movement Disorders Clinical Practice, EarlyView.
Abstract Background People with Parkinson's disease (PwP) face increased risks of complications and longer hospital stays compared to the general population. Four major factors contribute to increased morbidity and mortality during hospitalization: medication timing errors, administration of harmful medications, restricted mobility, and dysphagia ...
Ariane Veilleux Carpentier, Irene A. Malaty, Peter A. LeWitt, Hooman Azmi, Anne Brooks, Edward Pollak, Ellen L. Air, Heather Simpson, Jaime Thomas, Florian P. Thomas, Lisa Cocoziello, Sheera Rosenfeld, Michael S. Okun   +12 more
wiley   +1 more source