Results 51 to 60 of about 44,772 (320)

Elucidation of the Crystal Structures and Dehydration Behaviors of Ondansetron Salts

Crystals, 2019
In drug development, it is extremely important to evaluate the solubility and stability of solid states and to immediately determine the potential for development.
Ryo Mizoguchi, Hidehiro Uekusa
doaj   +1 more source

Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome

Clinical Case Reports, 2022
Ondansetron is an FDA‐approved selective serotonin 5‐HT3 receptor commonly indicated as an anti‐emetic agent for nausea and vomiting. It is rare to observe fatal reactions from ondansetron despite having no allergies or previous exposure.
Eden Firew, Helen Huang, Ayush Anand, Yonathan Aliye Asfaw, Charmy Parikh, Hamza Rafique Khan   +5 more
doaj   +1 more source

Severe acute dystonia induced by ondansetron in a paediatric patient: a case report

Emergency Care Journal
Ondansetron, a 5-HT3 serotonin receptor antagonist, is widely used to manage nausea and vomiting, particularly in postoperative recovery, chemotherapy, and paediatric gastroenteritis.
Kishore Nagaraju, Roshni Balachandran, Srilakshmi Ravindra Bhat, Venkatesh Karkada Srinivas, Srinivasan Ranganathan   +4 more
doaj   +1 more source

Hyoscine butyl-bromide versus ondansetron for nausea and vomiting during caesarean delivery under spinal anaesthesia. A randomized clinical trial

Egyptian Journal of Anaesthesia, 2023
Background The unopposed vagal activity with sympathetic block and maternal bradycardia that is likely to occur with phenylephrine infusion might be some causes of intraoperative nausea and vomiting (IONV) during spinal anaesthesia. We aimed at comparing
Mostafa Samy Abbas, Asmaa Shabaan Ahmed, Nawal Abd El-Aziz Gad El-Rab, Ahmed MA Sobh, Ahmed Aboulfotouh   +4 more
doaj   +1 more source

Ondansetron blocks wild-type and p.F503L variant small-conductance Ca2+-activated K+ channels.

American Journal of Physiology. Heart and Circulatory Physiology, 2018
Apamin-sensitive small-conductance Ca2+-activated K+ (SK) current ( IKAS) is encoded by Ca2+-activated K+ channel subfamily N ( KCNN) genes. IKAS importantly contributes to cardiac repolarization in conditions associated with reduced repolarization ...
J. Ko, Shuai Guo, Jonathan L Hassel, Patrícia B. S. Celestino-Soper, T. Lynnes, J. Tisdale, James Zheng, Stanley E Taylor, T. Foroud, Michael D. Murray, R. Kovacs, Xiaochun Li, Shien‐Fong Lin, Zhenhui Chen, M. Vatta, Peng-Sheng Chen, M. Rubart   +16 more
semanticscholar   +1 more source

Economic evaluation of ondansetron: Preliminary analysis using clinical trial data prior to price setting [PDF]

, 1992
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright © 1992 Macmillan Press Ltd.This study combines secondary analysis of efficacy and side-effect data from a randomised ...
Buxton, MJ, O'Brien, BJ
core   +1 more source

Effects of Modification of Pain Protocol on Incidence of Post Operative Nausea and Vomiting. [PDF]

, 2016
BackgroundA Perioperative Surgical Home (PSH) care model applies a standardized multidisciplinary approach to patient care using evidence-based medicine to modify and improve protocols.
Ahn, Kyle, Bahn, Esther, Calderon, Michael-David, Harrington, Brian, Rinehart, Joseph B, Schwarzkopf, Ran, Sharfman, Zachary T, Snir, Nimrod   +7 more
core   +2 more sources

Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs

European Journal of Organic Chemistry, EarlyView.
Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar, Perla Islas‐Jácome, Leonardo D. Herrera‐Zuñiga, Samuel Couve‐Bonnaire, Philippe Jubault, Eduardo González‐Zamora, Jean‐Philippe Bouillon, Alejandro Islas‐Jácome   +7 more
wiley   +1 more source

Ondansetron 8 mg and 4 mg with normal saline against post-operative headache and nausea/vomiting after spinal anesthesia: a randomized double-blind trial

Medical Gas Research, 2018
The study aims to evaluate the efficacy of ondansetron in preventing post-spinal headache, considering the high prevalence of the headache in pregnant women and the common use of the adjuvants for prophylaxis against post-operative nausea and vomiting ...
Shirin Pazoki, H. Modir, A. Kamali, Ashraf Zamani, Marzieh Shahidani   +4 more
semanticscholar   +1 more source

Comparison of the antiemetic effect of ramosetron with the combination of dexamethasone and ondansetron in middle ear surgery: A double-blind, randomized clinical study

Saudi Journal of Anaesthesia, 2013
Background: Postoperative nausea and vomiting (PONV) is a frequent complication of middle ear surgery. Ondansetron has been shown to be effective for early PONV and dexamethasone has been shown to be effective for late PONV.
Sameer Desai, M. C. B. Santosh, Rashmi Annigeri, V B Santoshi, Raghavendra Rao   +4 more
doaj   +1 more source