Results 121 to 130 of about 20,866,353 (270)

Housing circumstances of Indigenous households: tenure and overcrowding [PDF]

, 2014
In 2011, Indigenous households were about half as likely as other Australian households to own their home and more than 3 times as likely to be overcrowded, finds this report.

core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Fiscal Governance in a Shrinking Society: One-Person Households and the Transformation of Local Public Finance in Seoul

This article examines how the transition to a shrinking society— characterised by low fertility, population ageing, and the rapid growth of one-person households—affects local public finance in Seoul and explores directions for a new fiscal paradigm ...
Pil-Doo Kim, Center for Civic Politics Research, Hyun-Chool Lee   +2 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Comparison of Health Behaviors, Disease Prevalence between Middle Aged One-Person Households and Multi-Member Households in South Korea

, 2019
이 논문은 증가하는 중년 1인가구의 건강상태 파악에 주목한다. 특히 중년 1인가구의 건강행위 및 질병 이환을 다인가구 중년과 비교하는 것을 목적으로 한다. 이 논문에서는 중년 1인가구의 건강행태 및 질병 이환이 다인가구 중년보다 취약할 것이라고 가정하였다. 중년 1인가구와 다인가구 중년의 건강행태 및 질병 이환을 비교하기 위하여 2008년, 2012년, 2016년 지역사회건강조사자료를 활용하였다. 우리나라 중년 40~50대를 대상으로 인구사회학적 특성,
조영태, 이하나
core  

Subjektiver Überkonsum von Wohnraum: Empirische Evidenz für die Schweiz

Raumforschung und Raumordnung, 2018
In Switzerland, living space consumption per person has been increasing for years. Besides structural causes, the overconsumption of living space is one of the determinants.
Katia Delbiaggio, Gabrielle Wanzenried
doaj