Results 141 to 150 of about 1,198,194 (286)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Effects of Adjunctive EDTA and Air-Polishing Powders on Periodontitis-Affected Root Surfaces: A SEM Study. [PDF]

Medicina (Kaunas)
Ifrim ȘS, Cândea A, Soancă A, Roman A, Vesa Ș, Albu S, Șurlin P, Dinte E, Pall E, Ifrim C, Barbu-Tudoran L.   +10 more
europepmc   +1 more source

Single-Variable Calculus II

, 2012
This course is the second installment of Single-Variable Calculus. The student will explore the mathematical applications of integration before delving into the second major topic of this course: series.
The Saylor Foundation
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A numerical framework for fractional and fractal-fractional analysis of the Pehlivan chaotic system using Caputo derivative. [PDF]

Sci Rep
Vinoth R, Jayalakshmi M.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Risk prediction models for postoperative complications of urosepsis in patients with upper urinary calculi: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Wang J, Wu R, Zhang C, Cao X, Wang F, Zhang X.   +5 more
europepmc   +1 more source

Average value theorems for real functions of one variable

, 1990
Summary.
Konrad Raczkowski, Paweł Sadowski, Jarosław Kotowicz   +2 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Discrete stochastic maximal regularity. [PDF]

Math Ann
Evangelopoulos-Ntemiris F, Veraar M.
europepmc   +1 more source