Results 111 to 120 of about 1,118,522 (321)

Calcium and Magnesium in Ilam Drinking Water Sources during 2009-2013 using Geographic Information System (GIS)

open access: yesIranian Journal of Health, Safety and Environment, 2017
Physicochemical quality of water from the acceptability point of view is essential for consumers; protecting the health of consumers and maintenance of water supply systems. The aim of this study is to determine temporal and spatial variations of Calcium
Zabihollah Yousefi   +2 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Interaction between activity and movement control during one-leg standing in parameters of bone strength in patients with hip fractures—a cross-sectional study

open access: yesJournal of Orthopaedics, Trauma and Rehabilitation
Background/Purpose We aimed to investigate whether there is an interaction between life-space assessment (LSA) and movement control during one-leg standing on bone strength on the non-fractured side in patients with hip fracture. Methods Two-way analysis
Takuya Umehara   +7 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The article describes development of methods of quantitative determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy as well as an estimation of the statistical significance of differences in
O. N. Kolesnikova   +3 more
doaj  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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