Results 221 to 230 of about 1,010,293 (299)

Optimization of row and hill spacing patterns improved rice population structure and increased rice yield. [PDF]

Front Plant Sci
Dong L, Yang T, Ma L, Li Y.
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Role of endogenous serotonin in psychedelic-like effects of psilocybin in mice. [PDF]

Int J Neuropsychopharmacol
Erkizia-Santamaría I, Martínez-Álvarez N, Salinas-Novoa L, Meana JJ, Ortega JE.   +4 more
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

National Trends in Admissions, Treatments, and Outcomes for Dilated Cardiomyopathy (2016-2021). [PDF]

Med Sci (Basel)
Varughese VJ, Mohamed A, Nagesh VK, Atoot A.   +3 more
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Corrigendum: Nanocarrier-mediated RNAi of <i>CYP9E2</i> and <i>CYB5R</i> enhance susceptibility of invasive tomato pest, <i>Tuta absoluta</i> to cyantraniliprole. [PDF]

Front Plant Sci
Ullah F, G GP, Gul H, Panda RM, Murtaza G, Zhang Z, Huang J, Li X, Desneux N, Lu Y.   +9 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Polystyrene microplastics impair the function of human retinal microvascular endothelial cells and pericytes and increase vascular permeability <i>in vitro</i>. [PDF]

Front Med (Lausanne)
Yun JH.
europepmc   +1 more source