Results 121 to 130 of about 42,469,765 (329)

A diverse set of solubilized natural fibers drives structure-dependent metabolism and modulation of the human gut microbiota

mBio
Growing evidence suggests that inadequate dietary fiber intake, termed the “fiber gap,” is linked to disease states through disruption of the gut microbiota.
Maria X. Maldonado-Gomez, Katharine M. Ng, Riley A. Drexler, Alexandria M. S. Conner, Cory G. Vierra, Nithya Krishnakumar, Hannah M. Gerber, Zachary R. Taylor, Jenna L. Treon, Megan Ellis, Jada K. A. Garcia, James P. Cerney, David G. Chapin, Robnet T. Kerns, Angela M. Marcobal, Steven M. Watkins, Matthew J. Amicucci   +16 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The Question of HIV Vaccine: Why Is a Solution Not Yet Available?

Journal of Immunology Research
Ever since its discovery, human immunodeficiency virus type 1 (HIV-1) infection has remained a significant public health concern. The number of HIV-1 seropositive individuals currently stands at 40.1 million, yet definitive treatment for the virus is ...
Martina Libera, Valeria Caputo, Giulia Laterza, Louiza Moudoud, Alessio Soggiu, Luigi Bonizzi, Roberta A. Diotti   +6 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Anticompetitive Contracts in the U.K. Pay-TV Market [PDF]

contracts, raising rivals costs, pay ...
Author One David Harbord, Author Two Marco Ottaviani   +1 more
core  

Notes on One-loop Calculations in Light-cone Gauge [PDF]

, 2005
Charles B. Thorn
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

One-step green synthesis and characterization of plant protein-coated mercuric oxide (HgO) nanoparticles: antimicrobial studies

, 2015
Amlan Das, Avinash Marwal, Divya Sain, Vikram Pareek   +3 more
openalex   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

One Defence: one direction? The First Principles Review of Defence [PDF]

Overview: The recently released report of the First Principles Review of Defence, Creating One Defence, is set to reshape the Defence enterprise over the next few years.
Andrew Davies, Mark Thomson, Peter Jennings   +2 more
core