Results 121 to 130 of about 29,606,773 (297)

Watch one, do one, teach one [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2016
Marc, Gillinov   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

David Ralph : in captivity

open access: yes, 2008
Catalogue of an exhibition held at Arc One Gallery, Melbourne, Victoria, 12 February - 8 March 2008.Essay: Ashley ...
Arc One Gallery
core  

One-to-One Mappings [PDF]

open access: yesProceedings of the American Mathematical Society, 1972
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Heat : Pat Brassington

open access: yes, 2007
Catalogue of an exhibition held at Arc One Gallery, Melbourne, Victoria, 4 - 29 September 2007.Essay: Ashley ...
Arc One Gallery
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Evaluating the efficacy of reprocessing contaminated single use devices for re-use in intensive care unit in Ethiopia

open access: yesAntimicrobial Resistance and Infection Control
Background Single use devices (SUDs) are designed for single use. However, in low-income countries, they are often reprocessed and reused. Because these devices are intended for single use, no standardized protocol for reprocessing these devices ...
Yamirot Merga Duffa   +12 more
doaj   +1 more source

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