Results 171 to 180 of about 29,606,773 (297)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Essay by Adrian Parr. Exhibited at ARC One Gallery, 5-30 August 2003. "This project has been assisted by the Commonwealth through the Australia Council, its Arts Funding and Advisory Board"--Back ...
Arc One Gallery
core
Editorial Note: C4b Binding Protein Binds to CD154 Preventing CD40 Mediated Cholangiocyte Apoptosis: A Novel Link between Complement and Epithelial Cell Survival. [PDF]
PLOS OneEditors.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A Practical Guide to Optimal Adaptive Two-Stage Designs for Various Endpoint Types. [PDF]
Bruder N, Meis J, Pilz M, Kieser M.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Editorial Note: Significant increase in eco-efficiency of China's grain production from 2000 to 2022: Trend changes, typological evolution, and driving factors. [PDF]
PLOS One Editors.
europepmc +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Editorial Note: Aquaporin expression contributes to human transurothelial permeability in vitro and is modulated by NaCl. [PDF]
PLOS One Editors.
europepmc +1 more source

