Results 181 to 190 of about 40,161,086 (406)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Assessing One Health integration in Somalia’s school curriculum for future pandemic preparedness
CABI One HealthBackground: The COVID-19 pandemic has highlighted the need for a holistic health approach, emphasizing the interconnectedness of human, animal, plant, and environmental health.
Ahmed Abdulkadir Hassan-Kadle +2 more
doaj +1 more source
One Health: A Strategic Paradigm Shift to Propel Iran’s Vaccine Industry into its Second Century [PDF]
Zahra Baradaran‐Seyed
openalex +1 more source
Evaluation of the Specialist Community Public Health Nursing Peripatetic Assessment Model [PDF]
, 2017 The Health Visitor Implementation Plan 2011-15: a call to action, called for an additional 4200 health visitors to be trained by 2015. To accommodate larger numbers of students, specialist community public health nursing (SCPHN) programmes across the UK ...
Brook, J. +3 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Evaluation of milking performance following 2 different teat-preparation routines
Journal of Dairy Science: The aim of this study was to investigate whether the use of an iodine-based predip solution and paper towel (dip routine) reduces the incidence of delayed milk ejection and the recorded vacuum at the teat end, compared with a proprietary teat wipe ...
H.J. Williams +5 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics
Advanced ScienceMicro‐ and nanoplastics, particularly those derived from food‐contact materials like polyethylene terephthalate (PET), can damage gut barriers, making the gastrointestinal system more vulnerable to inflammation and infections.
Wenxin Chen +9 more
doaj +1 more source
One Health and human health [PDF]
Chinese Science Bulletin, 2021 Qiang Deng, Jiahai Lu
openaire +1 more source