Results 211 to 220 of about 7,692,761 (259)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2023 As its name suggestes, Global Health aims to approach health issues broadly and comprehensively both from a geographical and a conceptual point of view. In this demand, the human–animal–ecosystem interface cannot be left behind: the One Health approach, an improved integration among disciplines that enhances cross-sectoral collaboration between ...
Cardinale, Eric, Bernotti, Ilaria
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Current Biology
Bertram and colleagues introduce the One Health concept, an interdisciplinary framework that aims to sustainably advance and safeguard the health of humans, animals, and the environment.
Michael G, Bertram +4 more
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Bertram and colleagues introduce the One Health concept, an interdisciplinary framework that aims to sustainably advance and safeguard the health of humans, animals, and the environment.
Michael G, Bertram +4 more
+5 more sources
2021
Abstract This chapter presents examples that demonstrate how economic analysis involving human and animal health sectors has become a central element for providing evidence of the added value of a One Health approach, then reflects on the new developments in One Health, in particular, approaches based on systems thinking, and their implications
Häsler, Barbara +5 more
openaire +2 more sources
Abstract This chapter presents examples that demonstrate how economic analysis involving human and animal health sectors has become a central element for providing evidence of the added value of a One Health approach, then reflects on the new developments in One Health, in particular, approaches based on systems thinking, and their implications
Häsler, Barbara +5 more
openaire +2 more sources
Bioethics, 2021
AbstractOne health has brought to the fore connections—between human culture and nature—that underlie healthy (and unhealthy) ecological niches. Like other emerging environmental concepts—eco‐health, one medicine and planetary health—one health merges scientific evidence with reasons for sustaining a healthy environment.
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AbstractOne health has brought to the fore connections—between human culture and nature—that underlie healthy (and unhealthy) ecological niches. Like other emerging environmental concepts—eco‐health, one medicine and planetary health—one health merges scientific evidence with reasons for sustaining a healthy environment.
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Veterinary Record, 2014
NEWS of the invention of the wheel seems to have escaped those busy reinventing or redefining it. The article by Paul Gibbs ( VR , January 25, 2014, vol 174, pp 85-91) is welcome for the wealth of encouraging detail that it provides, but its omissions are astonishing.
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NEWS of the invention of the wheel seems to have escaped those busy reinventing or redefining it. The article by Paul Gibbs ( VR , January 25, 2014, vol 174, pp 85-91) is welcome for the wealth of encouraging detail that it provides, but its omissions are astonishing.
openaire +4 more sources
Veterinary Record, 2013
THE Queensland University of Technology is one of the first universities in the southern hemisphere to develop a focus on …
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THE Queensland University of Technology is one of the first universities in the southern hemisphere to develop a focus on …
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One Health, Global Health e Planetary Health
SALUTE E SOCIETÀOver the past two decades, the ecological approach to health has emphasized the interconnectedness between human health, biodiversity, ecosystem integrity, and socioeconomic conditions. As these systems are deeply interlinked, social and environmental justice must be considered interdependent, since crises in one area have the potential to impact other
Romizi Roberto +2 more
openaire +1 more source