Results 191 to 200 of about 5,500,235 (250)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Upper Extremity Fractures in Older Medicolegal Patients: Radiologic Characteristics and Factors Associated with Permanent Functional Impairment. [PDF]

Diagnostics (Basel)
Çelikel A, Şimşek Ü, Karbeyaz K, Özkök A.   +3 more
europepmc   +1 more source

Evidence in the Age of Algorithms: Redefining Emergency Medicine Research. [PDF]

Open Access Emerg Med
Baez AA.
europepmc   +1 more source

Billing E-Visits and Patient Medical Advice Requests in a Large Academic Health Center.

JAMA Netw Open
Bhatla A, Hughes HK, McGuire MJ, Hasselfeld BW.   +3 more
europepmc   +1 more source