Results 1 to 10 of about 863 (65)
Yumurtalık Kanseri Hücre Soylarında CIP2A Onkogeni Mutasyonlarının Taranması [PDF]
Amaç: Kanserle ilişkili genetik değişimlerin belirlenmesi erken tanı, hastalığın takibi ve hedefe yöneliktedavi yaklaşımlarının geliştirilmesi açısından önem taşımaktadır. CIP2A, birçok insan kanserleri ileilişkilendirilmiş yeni tanımlanmış bir onkoproteindir.
YAŞAR ŞİRİN, Duygu, BİLGEN, Türker
openaire +5 more sources
Expression of Bcl-2 protein and the amplification of c-myc gene in patients with chronic myeloid leukemia [PDF]
Background/Aim. Chronic myeloid leukemia (CML) represents a malignant myeloproliferative disease developed out of pluripotent hematopoietic stem cell that contains the fusion bcr-abl gene. Disorders that occur in the process of apoptosis represent one of
Brajušković Goran +5 more
core +1 more source
Immunohistochemical analysis of angiogenesis in invasive ductal breast carcinoma with correlations to clinic pathological factor [PDF]
Background/aim: Angiogenesis is the formation of new vessels from preexisting ones. The aim of our study was to determine the relevance of tumor-induced angiogenesis, its correlation with some of the commonly used clinical, pathological factors and the ...
Ivković-Kapicl Tatjana +3 more
core +1 more source
Oncogenic Aspects HPV Infections of the Female Genital Tract [PDF]
Humani papilomavirus (HPV) glavni je etiološki čimbenik zloćudne preobrazbe vrata maternice. Najvećim dijelom zloćudna preobrazba stidnice i rodnice također je inducirana ovim virusom. Humani papilomavirusi odlično su prilagođeni svom prirodnom domaćinu,
Ante Ćorušić +3 more
core +1 more source
New drugs in cancer chemotherapy [PDF]
Tumorske stanice su osjetljivije od normalnih stanica na kemoterapijske lijekove. Cilj lijekova koji se koriste u kemoterapiji tumora je izazivanje apoptoze tumorskih stanica. U ovom radu izložen je pregled antitumorskih lijekova.
Hanžić, Nikolina
core +2 more sources
onkogeni potencijal i putevi najčešćih zagađivača vode
In the last two centuries since the beginning of industrialization, the world has developed rapidly, which has contributed to the development of water supply networks and the improvement of the quality of drinking water. At the same time, as a result of the increasing development of industry, air and water pollution is also increased.
Kurevija, Tomislav +3 more
openaire +1 more source
p53 tumor suppresor gene [PDF]
Gen p53 otkriven je 1979. godine i prvi je otkriveni tumor supresorski gen. Njegova glavna uloga u organizmu je sprječavanje nastanka tumora i to na način da na određene podražaje kao što su oštećenje DNA, hipoksija ili aktivacija onkogena može ...
Pažur, Kristijan
core +2 more sources
Apoptosis and non-apoptotic types of cell death during tumorigenesis [PDF]
Višestanični eukariotski organizmi imaju reguliran proces stanične smrti. Ukoliko je stanična smrt onemogućena ona može biti uzrok nastanka različitih bolesti pa tako i tumora.
Buršić, Veronika
core +2 more sources
Onkogeni potencijal i putevi najčešćih zagađivača zraka
Air pollution is one of the largest global environmental and public health problems.In addition to natural causes of pollution such as wildfires and volcanoes, there is an increasing number of artificially produced particles and gases that cause pollution.
Lukić, Matea +3 more
openaire +1 more source
The p53 family of genes in development and tumor formation [PDF]
Tumor supresorski gen p53 ima kriti čnu ulogu u kontroli staničnog rasta i održavanju genetske stabilnosti. Ove aktivnosti posljedica su činjenice da p53 stvara tetramere koji se vežu za određeni slijed na DNA i akti viraju transkripciju.
Anđela Horvat +2 more
core +1 more source

