Results 1 to 10 of about 863 (65)

Yumurtalık Kanseri Hücre Soylarında CIP2A Onkogeni Mutasyonlarının Taranması [PDF]

open access: yesAkdeniz Medical Journal, 2018
Amaç: Kanserle ilişkili genetik değişimlerin belirlenmesi erken tanı, hastalığın takibi ve hedefe yöneliktedavi yaklaşımlarının geliştirilmesi açısından önem taşımaktadır. CIP2A, birçok insan kanserleri ileilişkilendirilmiş yeni tanımlanmış bir onkoproteindir.
YAŞAR ŞİRİN, Duygu, BİLGEN, Türker
openaire   +5 more sources

Expression of Bcl-2 protein and the amplification of c-myc gene in patients with chronic myeloid leukemia [PDF]

open access: yes, 2006
Background/Aim. Chronic myeloid leukemia (CML) represents a malignant myeloproliferative disease developed out of pluripotent hematopoietic stem cell that contains the fusion bcr-abl gene. Disorders that occur in the process of apoptosis represent one of
Brajušković Goran   +5 more
core   +1 more source

Immunohistochemical analysis of angiogenesis in invasive ductal breast carcinoma with correlations to clinic pathological factor [PDF]

open access: yes, 2006
Background/aim: Angiogenesis is the formation of new vessels from preexisting ones. The aim of our study was to determine the relevance of tumor-induced angiogenesis, its correlation with some of the commonly used clinical, pathological factors and the ...
Ivković-Kapicl Tatjana   +3 more
core   +1 more source

Oncogenic Aspects HPV Infections of the Female Genital Tract [PDF]

open access: yes, 2009
Humani papilomavirus (HPV) glavni je etiološki čimbenik zloćudne preobrazbe vrata maternice. Najvećim dijelom zloćudna preobrazba stidnice i rodnice također je inducirana ovim virusom. Humani papilomavirusi odlično su prilagođeni svom prirodnom domaćinu,
Ante Ćorušić   +3 more
core   +1 more source

New drugs in cancer chemotherapy [PDF]

open access: yes, 2010
Tumorske stanice su osjetljivije od normalnih stanica na kemoterapijske lijekove. Cilj lijekova koji se koriste u kemoterapiji tumora je izazivanje apoptoze tumorskih stanica. U ovom radu izložen je pregled antitumorskih lijekova.
Hanžić, Nikolina
core   +2 more sources

onkogeni potencijal i putevi najčešćih zagađivača vode

open access: yes, 2023
In the last two centuries since the beginning of industrialization, the world has developed rapidly, which has contributed to the development of water supply networks and the improvement of the quality of drinking water. At the same time, as a result of the increasing development of industry, air and water pollution is also increased.
Kurevija, Tomislav   +3 more
openaire   +1 more source

p53 tumor suppresor gene [PDF]

open access: yes, 2011
Gen p53 otkriven je 1979. godine i prvi je otkriveni tumor supresorski gen. Njegova glavna uloga u organizmu je sprječavanje nastanka tumora i to na način da na određene podražaje kao što su oštećenje DNA, hipoksija ili aktivacija onkogena može ...
Pažur, Kristijan
core   +2 more sources

Apoptosis and non-apoptotic types of cell death during tumorigenesis [PDF]

open access: yes, 2018
Višestanični eukariotski organizmi imaju reguliran proces stanične smrti. Ukoliko je stanična smrt onemogućena ona može biti uzrok nastanka različitih bolesti pa tako i tumora.
Buršić, Veronika
core   +2 more sources

Onkogeni potencijal i putevi najčešćih zagađivača zraka

open access: yes, 2022
Air pollution is one of the largest global environmental and public health problems.In addition to natural causes of pollution such as wildfires and volcanoes, there is an increasing number of artificially produced particles and gases that cause pollution.
Lukić, Matea   +3 more
openaire   +1 more source

The p53 family of genes in development and tumor formation [PDF]

open access: yes, 2010
Tumor supresorski gen p53 ima kriti čnu ulogu u kontroli staničnog rasta i održavanju genetske stabilnosti. Ove aktivnosti posljedica su činjenice da p53 stvara tetramere koji se vežu za određeni slijed na DNA i akti viraju transkripciju.
Anđela Horvat   +2 more
core   +1 more source

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