Results 141 to 150 of about 16,870 (170)

Uncertainty‐Guided Selective Adaptation Enables Cross‐Platform Predictive Fluorescence Microscopy

Advanced Intelligent Discovery, EarlyView.
Deep learning models often fail when transferred to new microscopes. A novel framework overcomes this by selectively adapting the early layers governing low‐level image statistics, while freezing deep layers that encode morphology. This uncertainty‐guided approach enables robust, label‐free virtual staining across diverse systems, democratizing ...
Kai‐Wen K. Yang, Andrew Bai, Alexandra Bermudez, Yunqi Hong, Zoe Latham, Iris Sloan, Michael Liu, Vishrut Goyal, Cho‐Jui Hsieh, Neil Y. C. Lin   +9 more
wiley   +1 more source

Soft X-rays with orbital angular momentum for resonant scattering experiments at Synchrotron SOLEIL. [PDF]

J Synchrotron Radiat
Carrara P, Fortuna F, Delaunay R, Vila-Comamala J, Rösner B, David C, Pizzini S, Fourniols C, Vila L, Pancaldi M, Spezzani C, Capotondi F, Nonnon P, Fanciulli M, Ruchon T, Jaouen N, Popescu H, Sacchi M.   +17 more
europepmc   +1 more source

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

Advanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha, Jesus Gil, Pedro J. Ballester   +2 more
wiley   +1 more source

Exploration of the mechanism of Tongmai Jiangzhuo Decoction in treating atherosclerosis based on network pharmacology and experimental validation. [PDF]

Am J Transl Res
Xu Y, Shi H, Ma C, Zhao Y, Niu Z, Gao X, Zhang Y, Li X, Luan Y, Xia J, Wang G.   +10 more
europepmc   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Astragaloside IV alleviates chronic low-grade inflammation in polycystic ovary syndrome by acting on IL-6R and inhibiting the NLRP3 inflammasome. [PDF]

Sci Rep
Shi H, Liu Q, Zhong L, Zhou M, Zhang T, Lei M.   +5 more
europepmc   +1 more source

Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma. [PDF]

Gut
Prawira A, Xu H, Mei Y, Leow WQ, Nasir NJM, Reolo MJ, Otsuka M, Rahbari M, Chen Z, Weerasooriya M, Abdullah LB, Wu J, Hazirah SN, Wasser M, Chung A, Goh BK, Chow PK, Albani S, Lee J, Lim TKH, Zhai W, Dan YY, Goh GB, Heikenwälder MF, Zhang Y, Dasgupta R, Tai WMD, Liu H, Chen J, Chew V.   +29 more
europepmc   +1 more source

Enhancing patient-specific quality assurance in MR-guided radiation therapy: A fluence-based method using log files. [PDF]

J Appl Clin Med Phys
Yuan K, Man-Hin Cheung M, Lee L.
europepmc   +1 more source

Pseudo-Landau levels splitting triggers quantum friction at folded graphene edge. [PDF]

Nat Commun
Gao X, Gong Z, Li H, Liu Z, Yan W, Zheng Q, Ren K, Wu W, Zhang J.   +8 more
europepmc   +1 more source

Computational pharmacovigilance of tranexamic acid: implications for intracerebral hemorrhage based on FAERS database and network toxicology. [PDF]

Front Pharmacol
Wu JW, Shen CC, Wang P, Wang BX, Chen CY, Miao ZL, Zhao XD, Gao W.   +7 more
europepmc   +1 more source