Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
To see or not to see the vet: A vignette-based study of decision-making by UK dog owners regarding seeking veterinary care for commonly presenting conditions. [PDF]
PLoS OneFarrow M, O'Neill DG, Packer RMA.
europepmc +1 more source
Advanced Science, EarlyView.An ionic liquid‐based shear‐thickening fluid (ILSTF) exhibits lubricated dynamics from strong shear thickening to impact‐triggered jamming. A persistent nanometric solvation layer around silica governs both the shear thickening saturation in rheology and jamming front propagation under dynamic impact compression.
Yiran Wu +6 more
wiley +1 more source
Transmission of Radio‐Frequency Waves and Nuclear Magnetic Resonance in Lanthanum Superhydrides
Advanced Science, EarlyView.1H NMR and radio‐frequency transmission measurements of lanthanum superhydrides at 165 GPa reveals a transition at 260–280 K by a strong suppression of the signal intensity, significant changes in NMR spectra, including a dramatic decrease of the relaxation rate 1/T1T, and pronounced shielding effect, which may have a superconducting nature.
Dmitrii V. Semenok +8 more
wiley +1 more source
Enabling and hindering aspects of the i²TransHealth e-health intervention for transgender and gender diverse people in Germany: a qualitative process evaluation. [PDF]
BMC Health Serv ResSchmidt F +5 more
europepmc +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Advanced Science, EarlyView.ABSTRACT Plastic food containers used in food delivery may pose underrecognized health risks by releasing micro‐ and nanoplastics (MNPs), especially when in contact with oil‐rich foods. Here, we show that cooking oil dramatically increased MNP release from polypropylene (PP) and polyethylene (PE)‐coated containers within 3 min of microwave heating ...
Ruwen Xie +17 more
wiley +1 more source
Trust in science during the COVID-19 pandemic: A typology of internet users in South Africa. [PDF]
PLoS OneReif A +3 more
europepmc +1 more source
Emerging Device Applications From Strong Light–Matter Interactions in 2D Materials
Advanced Science, EarlyView.Two‐dimensional semiconductors enable extremely compact optoelectronic devices such as solar cells, sensors, LEDs, and lasers. Their strong light–matter interactions allow efficient light emission, detection, and energy conversion. This review article discusses the recent progress in integrating these materials with optical cavities and nanostructures ...
Janani Archana K +7 more
wiley +1 more source
Design and Implementation Process in a Pilot Project to Improve a Community Health Survey Using Mixed-mode Methods. [PDF]
Jugan Geongang Gwa JilbyeongKo J +5 more
europepmc +1 more source
A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data
Advanced Science, EarlyView.SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang +5 more
wiley +1 more source