Results 81 to 90 of about 3,859,713 (313)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Ensuring security and integrity of data for online assessment

, 2009
Two challenges with online assessment are making sure data collected is secure and authenticating the\ud data source. The first challenge relates to issues such as network security, robustness against attack\ud and data management.
Armatas, Christine, Bernard Colbert, Colbert, Bernard, Christine Armatas   +3 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Student-Courses Collection

This collection collects data from students about their academic and training activities at Tecnologico de Monterrey, from 1996 to date. It consists of 61 variables that are represented in different categories, such as: - Subject administration (school,
IFE Data Hub
core   +1 more source

Methodological Challenges in Online Trials

, 2009
Health care and health care services are increasingly being delivered over the Internet. There is a strong argument that interventions delivered online should also be evaluated online to maximize the trial's external validity.
Thompson, Simon G, Murray, Elizabeth, Khadjesari, Zarnie, McCambridge, J, Kalaitzaki, Eleftheria, White, IR, Wallace, P, Murray, E, White, Ian R, McCambridge, Jim, Thompson, SG, Wallace, Paul, Kalaitzaki, E, Godfrey, C, Khadjesari, Z, Godfrey, Christine, White, Ian R., Thompson, Simon G.   +17 more
core   +1 more source

Online Banking Satisfaction in Italy - OBS project [PDF]

, 2020
The datasets provide information from a questionnaire that investigated customer satisfaction of some online banking services in Italy in May and September ...
Francesca Bassi, Guidolin, Mariangela, Paccagnella, Omar, Mariangela Guidolin, Omar Paccagnella, Bassi, Francesca   +5 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Features of Group Online Learning Behaviours Based on Data Mining

, 2022
With the development of information technology, how to scientifically and properly organizing and guiding learners to learn actively and efficiently has become a research subject for domestic and foreign scholars.
Lei, Wang, Tanbo , Zhu, Die, Wang
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source