Results 121 to 130 of about 954 (257)

A Three‐Dimensional Culture–Drug Sensitivity Test Predicts MDM2 Inhibitor–Sensitivity in SMARCB1/INI1‐Deficient Tumors

Cancer Science, EarlyView.
This study aimed to determine whether personalized selection of effective drugs for SMARCB1/INI1‐deficient tumors is feasible using in vitro drug sensitivity profiling. Drug sensitivity was assessed using a short‐term collagen gel–embedded three‐dimensional drug sensitivity test (3D‐DST) in tumors derived from SMARCB1/INI1‐deficient tumor cell line ...
Hiroaki Goto, Chiyoko Nishime, Takashi Ohtsu, Mieko Ito, Maiko Sagisaka, Takuya Naruto, Norihiko Kitagawa, Mio Tanaka, Masakatsu Yanagimachi, Yukihiko Hiroshima, Junko Takita, Yasuhide Hayashi, Yohei Miyagi   +12 more
wiley   +1 more source

LLM-Reflex-GeoKG: A reflexion-enhanced LLM framework for automated geographic knowledge graph construction. [PDF]

PLoS One
Wei Z, Chen G, Xu Y, Yang X, Cao M, Liao M.   +5 more
europepmc   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Online Information on Lymphedema: Systematic Review of the Quality of Online Patient Resources. [PDF]

J Cancer Educ
Kok C, Karamitros G, Lamaris GA, Karagoz H, Grant MP, Gokani V.   +5 more
europepmc   +1 more source

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco, David Uroz‐Torres, Ana Soriano‐Lerma, Miguel Soriano, Jose Antonio García‐Salcedo, Maria Teresa Arias‐Moliz   +5 more
wiley   +1 more source

Perceptions of chiropractic students on digital literacy skills at a South African university: A cross-sectional study. [PDF]

J Chiropr Educ
Pyper CN, Moore BA, Ismail F.
europepmc   +1 more source

Standards for Hospital Falls Prevention and Management: An International Comparative Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Background Hospital falls and associated injuries are a global issue associated with harm and significant costs to individuals and society, especially for older adults. Hospital standards specify the minimum level of care required to optimise patient safety, quality and outcomes. Standards are often used during hospital accreditation.
Jonathan P. McKercher, Casey L. Peiris, Claire Thwaites, Hazel Heng, Deborah Gleeson, Gillian Janes, Meg E. Morris   +6 more
wiley   +1 more source

Perceptions of assisted reproductive technologies in wildlife conservation: Public expectations and ethical implications across three EU countries. [PDF]

PLoS One
Biasetti P, Hildebrandt T, Seet S, Stejskal J, Giardullo P, Göritz F, Holtze S, Galli C, Šťastný M, de Mori B.   +9 more
europepmc   +1 more source

Targeting the miR‐224‐5p/PTEN pathway: A previously under‐characterized strategy to attenuate mesangial cell injury and predict prognosis in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Serum miR‐224‐5p levels are progressively elevated in diabetic nephropathy (DN) and serve as an independent predictor of a decline in eGFR of ≥30% over 2 years. Mechanistically, miR‐224‐5p directly targets PTEN 3’‐UTR, suppressing PTEN and the activation of the AKT pathway in high‐glucose‐stimulated mesangial cells.
Yanxia Gao, Xiaohui Zhang, Peng Lu, Qiang Wang   +3 more
wiley   +1 more source

References to unbiased sources increase the helpfulness of community fact-checks. [PDF]

Sci Rep
Solovev K, Pröllochs N.
europepmc   +1 more source