Results 161 to 170 of about 19,329 (299)

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

open access: yesThe FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson   +5 more
wiley   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

open access: yesThe FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou   +6 more
wiley   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl   +10 more
wiley   +1 more source

New Approach to Supporting Stakeholders in English Medium Instruction through a Global Online Community

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT With the internationalisation of higher education, English medium instruction (EMI) has become increasingly common in non‐English‐speaking contexts. However, research highlights a range of challenges in EMI implementation, including insufficient collaboration between content and language teachers, limited professional development opportunities
Jingwen Zhou, Nadia Lamprecht
wiley   +1 more source

Designing for Sustainability: Emerging Professional Roles and Capabilities for Designers in the 21st Century

open access: yesInternational Journal of Art &Design Education, EarlyView.
Abstract Design Practice is shifting towards transdisciplinary, collaborative and problem‐based approaches in response to complex challenges of a changing world including societal issues and the climate crisis. However, the nature of emerging roles for designers aiming to contribute to sustainability transitions, and the capabilities that empower ...
Charlotte Kessler, Janice Rieger
wiley   +1 more source

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